What causes tumoral calcinosis?
Tumoral calcinosis may be genetic, the result of prior traumatic injury, or the result of a metabolic derangement, most commonly chronic renal failure, which accounts for approximately 23% of cases. Onset is typically in the second decade of life, with a reported increased frequency in African Americans.
Is tumoral calcinosis painful?
An acquired autoimmune form of hyperphosphatemic tumoral calcinosis has also been reported. Periarticular tumoral calcinosis is the primary cause of disability in HFTC, leading to pain, reduced range-of-motion, and impaired physical function.
How is tumoral calcinosis diagnosed?
Diagnosis of TC is mainly based on imaging modalities. Plain radiographs show the typical appearance of amorphous, multilobulated and cystic calcifications in a peri-articular location[17]. Computed tomography helps in determining the extent and relations of individual lesions, and as a guide for surgical planning.
What causes calcification of the spine?
As people age, the ligaments of the spine can thicken and harden (called calcification). Bones and joints may also enlarge, and bone spurs (called osteophytes) may form. Bulging or herniated discs are also common. Spondylolisthesis (the slipping of one vertebra onto another) also occurs and leads to compression.
Is tumoral calcinosis cancerous?
Larger deposits form masses that are noticeable under the skin and can interfere with the function of joints and impair movement. These large deposits may appear tumor-like (tumoral), but they are not tumors or cancerous.
How is tumoral calcinosis treated?
Tumoral calcinosis is a familial disease, usually associated with hyperphosphatemia, that is manifested by the deposition of calcific masses around major joints. Surgical excision of the masses has been the only partially effective treatment.
Which organ is metastatic calcification typically associated with?
Metastatic calcification can occur widely throughout the body but principally affects the interstitial tissues of the vasculature, kidneys, lungs, and gastric mucosa. For the latter three, acid secretions or rapid changes in pH levels contribute to the formation of salts.
What is familial tumoral calcinosis?
Hyperphosphatemic familial tumoral calcinosis (HFTC) is a condition characterized by an increase in the levels of phosphate in the blood (hyperphosphatemia) and abnormal deposits of phosphate and calcium (calcinosis) in the body’s tissues.
Who treats tumoral calcinosis?
A nephrologist, a rheumatologist, and/or a hematologist should be consulted, as indicated by the underlying disease.
How do you get rid of calcium deposits on your back?
How is it treated?
- A specialist can numb the area and use ultrasound imaging to guide needles to the deposit. The deposit is loosened, and most of it is sucked out with the needle.
- Shock wave therapy can be done.
- The calcium deposits can be removed with an arthroscopic surgery called debridement (say “dih-BREED-munt”).
Is calcinosis hereditary?
Abstract. Arterial calcification is a common phenomenon in the elderly, in patients with atherosclerosis or renal failure and in diabetes. However, when present in very young individuals, it is likely to be associated with an underlying hereditary disorder of arterial calcification.
What is tumororal calcinosis of the cervical spine?
Background: Tumoral calcinosis (TC) is a disease of unknown etiology characterized by the presence of calcified masses in the juxta-articular regions of the extremities. Involvement of the cervical spine is very rare.
What is the pathophysiology of tumor calcinosis?
Tumoral calcinosis (TC) is a disease of unknown etiology characterized by the presence of calcified masses in the juxta-articular regions of the extremities. Involvement of the cervical spine is very rare.
Is surgical resection the treatment of choice for tumoral calcinosis?
Postoperatively, residual masses may disappear spontaneously, while new bone is formed in the erosive lamina and facet. Conclusion: The treatment of choice for TC, if the lesion causes progressive symptoms, is surgical resection. Keywords: Cervical spine, myelopathy, tumoral calcinosis INTRODUCTION