What are the doses of adenosine?
The first dose of adenosine should be 6 mg administered rapidly over 1-3 seconds followed by a 20 ml NS bolus. If the patient’s rhythm does not convert out of SVT within 1 to 2 minutes, a second 12 mg dose may be given in a similar fashion. All efforts should be made to administer adenosine as quickly as possible.
How do you prepare adenosine infusion?
Adenosine Infusion should be administered undiluted as a continuous peripheral intravenous infusion at a dose of 140 µg/kg/min for six minutes using an infusion pump. Separate venous sites for Adenosine Infusion and radionuclide administration are recommended to avoid an adenosine bolus effect.
When do you give IV adenosine?
Indications and Usage Intravenous Adenocard (adenosine injection) is indicated for the following. Conversion to sinus rhythm of paroxysmal supraventricular tachycardia (PSVT), including that associated with accessory bypass tracts (Wolff-Parkinson-White Syndrome).
What do you give after adenosine?
Subsequent doses start at 12 mg, also followed by 20-mL saline for rapid infusion. [6] The initial dose of adenosine is reduced to a 3 mg bolus if given through an intravenous line that accessed into the central circulation, those on dipyridamole or carbamazepine, or if the patient is a cardiac transplant recipient.
What is amiodarone used for in ACLS?
Amiodarone is primarily chosen for ACLS as the first-line antiarrhythmic agent for cardiac arrest. This is because it is effective in improving the rate of return of spontaneous circulation (ROSC) and improved ROSC to hospital admission in adults with refractory v-fib or pulseless v-tach.
How do you mix adenosine for FFR?
Pre-mixed bags of adenosine 1mg/ml (100mg in 100mL or 130mg in 130ml) should be used where possible. Slowly run through an appropriate giving set and attach to volumetric infusion pump. Infusion rates are listed in the following table. The usual dose is 140 micrograms/kg/min.
How do you dilute adenosine?
Adenosine preparation:
- SS = 6mg adenosine + 18mL of 0.9% sodium chloride.
- TS = Two separate syringes of adenosine and 20mL 0.9% sodium chloride.
- If conversion to NSR was not achieved, the dose of adenosine was increased to 12mg in both groups and given via the same administration method previously used.
What is Amiodarone 400mg used for?
Amiodarone is used to treat and prevent certain types of serious, life-threatening ventricular arrhythmias (a certain type of abnormal heart rhythm when other medications did not help or could not be tolerated. Amiodarone is in a class of medications called antiarrhythmics.
What is Amiodarone 200mg?
This medication is used to treat certain types of serious (possibly fatal) irregular heartbeat (such as persistent ventricular fibrillation/tachycardia). It is used to restore normal heart rhythm and maintain a regular, steady heartbeat. Amiodarone is known as an anti-arrhythmic drug.
How do you calculate Adenosine infusion rate?
NOTE: The adenosine infusion rate can be calculated from the following formula: Infusion rate (mL/min) = [0.140 (mg/kg/min) x total body weight (kg)] divided by the Adenoscan concentration (3 mg/mL). 140 mcg/kg/minute IV infused for 6 minutes for a total dose of 0.84 mg/kg.
What is the best dose of adenosine to take?
Dosing. All efforts should be made to administer adenosine as quickly as possible. A lower initial dose of 3mg should be used for patients taking dipyridamole or carbamazepine as these two medications potentiate the effects of adenosine.
What is the molecular formula of adenosine?
Adenosine PubChem CID 60961 Structure Find Similar Structures Chemical Safety Laboratory Chemical Safety Summary (LCSS Molecular Formula C10H13N5O4 Synonyms adenosine 58-61-7 Adenocard Adenoscan Ad
What are the possible adverse effects of adenosine?
Because adenosine decreases conduction through the AV node, first-, second-, or third-degree heart block are possible effects. If a patient develops a high-level block after the initial dose of adenosine, subsequent doses should not be given.