What is the difference between Wistar and Sprague Dawley?
Wistar Rats – Long ears, tail length shorter than body length and wider head. Sprague Dawley Rats – Longer and Narrower head, tail longer than body (may equal to body length).
What is the significance of the Wistar rat?
The Wistar rat is an outbred albino rat. This breed was developed at the Wistar Institute in 1906 for use in biological and medical research, and is notably the first rat developed to serve as a model organism at a time when laboratories primarily used the house mouse (Mus musculus).
How long do Wistar rats live?
The maximum lifespan of the Wistar strain, for example, is about 1200 days (3.2 years) for males and 1400 days (3.8 years) for females. Median lifespan for the Wistar rat is 850 days for males and 900 days for females (Ghirardi et al. 1995 ).
Why Wistar rats are used in research?
Wistar albino rats were used for this study because their genetics, biological and behavioral characteristics are closely related to that of humans [61] .
What is the difference between albino rats and Wistar rats?
Difference between “Wistar” And “Sprague Dawley rats”: Wistar rat: The Wistar rat is an outbred albino rat. The Wistar rat is currently one of the most popular rats used for laboratory research. It is characterized by its wide head, long ears, and a tail length that is always less than its body length.
Are Sprague Dawley rats inbred?
In the rat, Sprague-Dawley and Wistar outbred stocks accounted for 86% of the total. The most widely used inbred strains were F344 and LEW, which accounted for 11% of hits.
Why do scientists use albino rats?
Sprague Dawley (albino rats) are used for this project because they will eat any food typically eaten by humans; they have a digestive system similar to humans; they are small, clean, gentle and easily caged animals; they can safely and easily be handled; they do no transmit disease to humans; and they grow quickly and …
Are lab rats inbred?
All laboratory rats are part of the same species: the Norway, or brown, rat. Many rats used in research and science are part of highly inbred strains, so that all the animals are extremely similar to each other genetically, reducing variability [source: RatBehavior.org].
How old is a 300g rat?
between 57 and 70 days
Thus, a 300 g male Sprague Dawley rat can be between 57 and 70 days of age, depending on the vendor and colony (Charles River SD SAS, 67 days; Harlan SD, 57 days, Harlan CD, 70 days).
Why do rats only live 2 years?
Domesticated rats have a longer lifespan than that of wild rats. Because domesticated rats are protected from predators and have ready access to food, water, shelter, and medical care, their average lifespan is around two to three years, in contrast to wild R. norvegicus which average a lifespan of less than one year.
How are lab rats killed?
Rats and mice used in aging studies often live out their natural lives, but most lab rodents are terminated at the end of a study. Some are killed via lethal injection or decapitated with strict guidelines to reduce pain and suffering, but most often, they are suffocated in cages with carbon dioxide.
How much do Sprague Dawley rats cost?
SD Females
| Age in Weeks | Quantity |
|---|---|
| 1-999 | |
| 5 to 6 | $30.00 |
| 7 to 8 | $44.00 |
| 9 to 10 | $46.00 |