How do you give unfractionated heparin?
UFH is administered in the hospital via an intravenous (IV) catheter inserted into an arm vein or as a subcutaneous injection under the skin. The initial dosage is determined by body weight.
How do you administer low molecular weight heparin?
Although LMWH and UFH work similarly to inhibit clotting factors, LMWH can be self-administered at home via subcutaneous (under the skin) injection and does not require regular blood monitoring necessary for UFH treatment. As with all heparins, LMWH dosing is based on a patient’s weight.
When do you bolus heparin?
Pharmacology of Unfractionated Heparin If an immediate anticoagulant effect is required, the initial dose should be accompanied by an IV bolus injection, because the anticoagulant effect of SC heparin is delayed for 1 to 2 hours.
How do you titrate heparin?
- Heparin Infusion Rate: 25,000 units = 1500 units/hour.
- 500ml.
- X (ml/hour)
- 25,000 units (X ml/hr) = 750,000.
- X ml/hr = 750,000.
- 25,000.
- X = 30 ml/hour.
When do you use unfractionated heparin vs LMWH?
Because LMWH has more predictable pharmacokinetics and anticoagulant effect, LMWH is recommended over unfractionated heparin for patients with massive pulmonary embolism, and for initial treatment of deep vein thrombosis.
Can LMWH be given IV?
LMWH could be intravenously (IV) administrated to patients on hemodialysis or with unstable angina or flat Q-wave myocardial infarction, which is followed by subcutaneous (SC) administration. Sometimes, LMWH given by continuous infusion (CI) was compared with SC administration for safety.
Why do we give heparin bolus?
Intravenous heparin therapy is often used in patients presenting with transient ischemic attack (TIA) or stroke as either bridging therapy for anticoagulation with warfarin, or as primary therapy in suspected intracranial arterial dissection, crescendo TIAs, or suspected hypercoagulable states.
How fast do you push heparin?
Use a final heparin concentration of 0.5 units/mL to run at 1 mL/hour IV. Use a final heparin concentration of 0.5 units/mL running at a rate of 1 mL/hour IV for peripheral arterial catheters.
Why do you titrate heparin?
Laboratory values that indicate coagulation levels in the blood help determine the proper dose of anticoagulant medications.