When an incorrect base pair is Recognised DNA polymerase reverses its direction by how many base pairs of DNA to excise the mismatched base?
In bacteria, all three DNA polymerases (I, II and III) have the ability to proofread, using 3′ 5′ exonuclease activity. When an incorrect base pair is recognized, DNA polymerase reverses its direction by one base pair of DNA and excises the mismatched base.
What is direct repair of DNA?
Introduction. Direct repair is defined as the elimination of DNA and RNA damage using chemical reversion that does not require a nucleotide template, breakage of the phosphodiester backbone or DNA synthesis.
What is the most common type of DNA repair?
excision repair
Which mechanism is used to repair a chemically modified base in DNA?
a) A light-dependent repair mechanism carried out by an enzyme called DNA photolyase. The enzyme repairs UV damage (largely pyrimidine-pyrimidine dimers) by binding to the dimers and using light energy to cleave dimer cross-links. a) Base excision repair involves DNA glycosylases, enzymes that recognize abnormal bases.