What is the meaning of acarbose?
Definition of ‘acarbose’ a type of diabetes medicine taken orally to slow and reduce the supply of glucose to the blood.
What is the role of acarbose?
Acarbose works by slowing the action of certain chemicals that break down food to release glucose (sugar) into your blood. Slowing food digestion helps keep blood glucose from rising very high after meals.
What type of drug is acarbose?
Acarbose belongs to a class of drugs called alpha-glucosidase inhibitors. It works by slowing the action of certain enzymes that break food down into sugars. This slows down digestion of carbohydrates to keep your blood sugar from rising very high after you eat.
Does acarbose reduce cardiovascular risk?
Acarbose treatment was therefore associated with a relative risk reduction of 49% for cardiovascular events and an absolute risk reduction of 2.5% among IGT patients.
How long has acarbose been on the market?
Acarbose is one of only two approved alpha-glucosidase inhibitors (the other being miglitol), receiving its first FDA approval in 1995 under the brand name Precose (since discontinued).
When do you give acarbose?
Take acarbose at the beginning of a meal. The tablets can be chewed with your first mouthful of food, or swallowed with a drink of water. The most common side-effect is wind (flatulence). Remember to follow any advice you have been given about your diet.
Is acarbose effective?
Data synthesis: Acarbose is effective in reducing postprandial hyperglycemia. It does not stimulate endogenous insulin secretion and, therefore, will not cause hypoglycemia when used as monotherapy. The enhanced glycemic control achieved with acarbose is additive to that of sulfonylureas.
Is acarbose an insulin?
No, acarbose is not a type of insulin and has no effect on the amount of insulin in your body. Instead it lowers blood sugar by slowing the amount of sugar absorbed from the food you eat.
What are adverse effects of acarbose?
Common side effects may include: stomach discomfort, gas, bloating; mild diarrhea; or. mild skin rash or itching.
Does acarbose affect blood pressure?
We found that acarbose effectively attenuates the fall in blood pressure after meals in patients with severe autonomic failure, suggesting a potential therapeutic use in the treatment of PPH.
How does acarbose treat hypoglycemia?
How do they work? Acarbose works by blocking an enzyme that breaks down starchy carbohydrates (bread, potato, etc) to glucose in the intestine. This will reduce the amount of glucose your body absorbs from food and give your pancreas time to secrete more insulin to lower blood sugar after meals.
What does acarbose mean in English?
ac·ar·bose. n. A drug, C25H43NO18, that reduces blood glucose levels by inhibiting the breakdown of complex carbohydrates in the intestine and is used to treat type 2 diabetes. [a- + carb(o)- + -ose.] acarbose. a type of diabetes medicine taken orally to slow and reduce the supply of glucose to the blood.
Does acarbose cause liver damage?
Acarbose is an alpha glucosidase inhibitor which decreases intestinal absorption of carbohydrates and is used as an adjunctive therapy in the management of type 2 diabetes. Acarbose has been linked to rare instances of clinically apparent acute liver injury.
Why are there different opinions on the effectiveness of acarbose?
A possible explanation for the differing opinions is an observation that acarbose is significantly more effective in patients eating a relatively high carbohydrate Eastern diet. It is a starch blocker, and inhibits alpha glucosidase, an intestinal enzyme that releases glucose from larger carbohydrates.
Is there a generic version of acarbose?
Acarbose (INN) is an anti-diabetic drug used to treat diabetes mellitus type 2 and, in some countries, prediabetes. It is a generic sold in Europe and China as Glucobay (Bayer AG), in North America as Precose (Bayer Pharmaceuticals), and in Canada as Prandase (Bayer AG). It is cheap and popular in China, but not in the U.S.