What is the structure of erythromycin?
C37H67NO13
Erythromycin/Formula
What is the 6 methyl derivative of erythromycin?
The 6-O-methyl ether of erythromycin A, clarithromycin is a macrolide antibiotic used in the treatment of respiratory-tract, skin and soft-tissue infections. It is also used to eradicate Helicobacter pylori in the treatment of peptic ulcer disease.
What functional groups are in erythromycin?
Erythromycin A is an erythromycin that consists of erythronolide A having 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl and 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl residues attahced at positions 4 and 6 respectively. It is an erythromycin and a cyclic ketone.
Is erythromycin broad or narrow spectrum?
Penicillin, tetracycline and erythromycin are broad-spectrum drugs, effective against gram-positive and gram-negative microorganisms.
Where is erythromycin metabolized?
Erythromycin is metabolized in the liver, and its major metabolites are the demethylated product at the dimethylamino group, the N-oxide of the desosamine, and des-cladinose erythromycin, all of which have much reduced antibacterial potency. Erythromycin and its metabolites are eliminated mainly in bile.
What are erythromycin derivatives?
A second generation of erythronolide-modified derivatives: roxithromycin, clarithromycin, azithromycin, dirithromycin and flurithromycin, have been synthesized and have exhibited significant improvements in pharmacokinetic and/or microbiological features.
What is the chemical structure of azithromycin?
Azithromycin Monohydrate
| PubChem CID | 9897015 |
|---|---|
| Structure | Find Similar Structures |
| Chemical Safety | Laboratory Chemical Safety Summary (LCSS) Datasheet |
| Molecular Formula | C38H74N2O13 |
| Synonyms | Azithromycin Monohydrate 121470-24-4 UNII-JTE4MNN1MD JTE4MNN1MD AZITHROMYCIN DIHYDRATE More… |
What is the chemical name of erythromycin?
(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6- {[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}- 14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)- 5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}- 3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione
Erythromycin/IUPAC ID
Is erythromycin broad spectrum?
What are broad and narrow-spectrum antibiotics?
Antibiotics are the most commonly prescribed medicine in children. Narrow-spectrum antibiotics target a few types of bacteria. Broad-spectrum antibiotics target many types of bacteria. Both types work well to treat infections.
Which antibiotics are broad spectrum?
The main examples of broad spectrum antibiotics in humans are tetracycline, ofloxacin and chloramphenicol. Chloramphenicol is found to be rapidly absorbed from the gastro-intestinal tract and hence can be given orally in case of typhoid, pneumonia and dysentery.
What are the most common uses for Erythromycin stearate?
Erythromycin stearate is the tablet form of a medication used in the treatment of bacterial infections and bacteria-related illnesses. It is a very specific form of medication and will only work on conditions such as bacterial infections of the skin and sinuses, strep throat, and Lyme disease.
What is the usual dose of erythromycin for skin infections?
The usual dosage is 30 to 50 mg/kg/day, in equally divided doses. For more severe infections this dosage may be doubled but should not exceed 4 g per day.
Does erythromycin affect human cells?
Erythromycin, like all macrolide antibiotics, prevents bacterial cells from growing and multiplying by interfering with their ability to make proteins while not affecting human cells.
Is erythromycin an antihistamine?
Erythromycin is a macrolide antibiotic which has an antimicrobial spectrum similar to or slightly wider than that of penicillin, and is often used for people who have an allergy to penicillins.