What is EE4A regimen?

What is EE4A regimen?

The standard treatment for these patients is removal of the kidney tumor then treatment with 2 anti-cancer drugs (chemotherapy), vincristine and dactinomycin, for a period of about 19 weeks. This is called regimen EE4A.

Is a Wilms tumor curable?

Wilms tumor is a rare kidney cancer that is highly treatable. Most kids with Wilms tumor survive and go on to live normal, healthy lives. Also known as nephroblastoma, Wilms tumor can affect both kidneys, but usually develops in just one.

Where is neuroblastoma located?

Most neuroblastomas begin in the abdomen, either in an adrenal gland or in sympathetic nerve ganglia. Most of the rest start in sympathetic ganglia near the spine in the chest or neck, or in the pelvis.

How is neuroblastoma diagnosed?

To diagnose neuroblastoma, your child’s provider will do a physical and neurological examination. A neurological exam checks your child’s nerve function, reflexes and coordination. Your child’s provider may order several tests to confirm a diagnosis and see if the cancer has spread.

Can Wilms tumor come back?

Most relapses (about 85%) occur within two years of diagnosis of the original Wilms’ tumour, but for some children it can come back later than this. For children who relapse, their treatment will depend on what treatment they have already had and what their cancer looks like under the microscope (histology)[1].

Why do babies get neuroblastoma?

What causes neuroblastoma? Neuroblastoma happens when immature nerve tissues (neuroblasts) grow out of control. The cells become abnormal and continue growing and dividing, forming a tumor. A genetic mutation (a change in the neuroblast’s genes) causes the cells to grow and divide uncontrollably.

Is neuroblastoma curable?

Neuroblastoma grows and reacts differently to treatment in different people. This is called the disease’s clinical behavior. Some children are cured with surgery alone or surgery with chemotherapy (see Types of Treatment). Others have a very aggressive disease that is resistant to treatment and difficult to cure.