What does CytomX Therapeutics do?
CytomX is a different kind of clinical-stage biopharmaceutical company—intent on revolutionizing the way we treat cancer. Our distinctive Probody® therapeutics are progressing through the clinic with the promise of unlocking the full potential of more potent, less toxic anti-cancer medications.
What is Probody Therapeutics?
Probody therapeutics, a new class of recombinant, proteolytically activated antibody prodrugs are in early development and are designed to exploit the hallmark of dysregulation of tumor protease activity to deliver their therapeutic effects within the tumor microenvironment (TME) rather than peripheral tissue.
What is a Probody drug conjugate?
A probody-drug conjugate (PDC) composed of a monoclonal antibody directed against the transferrin receptor 1 (TFR1; TRP1; CD71), linked to a proprietary masking peptide that covers the active antigen-binding site of the antibody through a protease-cleavable linker, and conjugated, via a valine-citrulline (VC) peptide …
Is CytomX a public company?
CytomX’s common stock is traded under the ticker symbol “CTMX” on The NASDAQ Global Market. CytomX’s initial public offering was in September 2015.
What does surface oncology do?
Surface Oncology is a clinical-stage immuno-oncology company focused on using its specialized knowledge of the biological pathways critical to the immunosuppressive tumor microenvironment (TME) for the development of next-generation therapies to help patients suffering with cancer.
What is a Probody?
Abstract. Probodies are proteolytically activated antibodies engineered to remain inert until activated locally in diseased tissue. In principle, any therapeutic antibody can be converted into Probody™ form.
What does Probody mean?
Probody means an Antibody linked to a Substrate and a Mask that is claimed or covered by CytomX Technology, where such Antibody is not conjugated to a Payload using a Linker. Probody means a recombinant Antibody linked with a Substrate and a Mask.
Is CytomX a good stock to buy?
CytomX Therapeutics has received a consensus rating of Buy. The company’s average rating score is 2.60, and is based on 4 buy ratings, no hold ratings, and 1 sell rating.
Is CTMX a buy?
A company with a P/E ratio of 40 and a growth rate of 50% would have a PEG ratio of 0.80 (40 / 50 = 0.80)….Momentum Scorecard. More Info.
| Zacks Rank | Definition | Annualized Return |
|---|---|---|
| 1 | Strong Buy | 25.42% |
| 2 | Buy | 19.05% |
| 3 | Hold | 10.68% |
| 4 | Sell | 6.41% |
Where is surface Oncology located?
Cambridge, Massachusetts
Surface Oncology is headquartered at 50 Hampshire Street in Cambridge, Massachusetts.
Why is surf stock dropping?
Shares of Surface Oncology (NASDAQ:SURF) were down by 13.6% as of 3:32 p.m. EST on Thursday. The decline came after the company announced a deal with GlaxoSmithKline (NYSE:GSK) to license its preclinical program SRF813 for $85 million up front.
Is Surf a buy or sell?
Surface Oncology has received a consensus rating of Buy. The company’s average rating score is 3.00, and is based on 4 buy ratings, no hold ratings, and no sell ratings.