What does PRDX2 mean?

What does PRDX2 mean?

PRDX2 (Peroxiredoxin 2) is a Protein Coding gene. Diseases associated with PRDX2 include Hemolytic Anemia and In Situ Carcinoma . Among its related pathways are Glucose / Energy Metabolism and DAG and IP3 signaling .

Can silencing of PRDX2 prevent non-small cell lung cancer?

Silencing of PRDX2 Inhibits the Proliferation and Invasion of Non-Small Cell Lung Cancer Cells. Peroxiredoxin 2 is highly expressed in human oral squamous cell carcinoma cells and is upregulated by human papillomavirus oncoproteins and arecoline, promoting proliferation.

What is prx2 in hepatocellular cancer?

Prx II plays a key role in the cancer stem cell self-renewal of hepatocellular carcinoma cells through redox regulation. Peroxiredoxin-2 (PRDX2) and hemoglobin-subunits proteins, which are closely involved in the response to oxidative stress. High PRDX2 expression is associated with colorectal cancer progression.

What is the role of prprdx2 in esophageal cancer?

PRDX2 plays an oncogenic role in esophageal squamous cell carcinoma via Wnt/beta-catenin and AKT pathways. Celastrol induces ROS-mediated apoptosis via directly targeting peroxiredoxin-2 in gastric cancer cells.