What was sulfathiazole used for?
Sultrin (sulfathiazole, sulfacetamide and sulfabenzamide) Cream is a topical antibacterial preparation used to treat vaginitis caused by Haemophilus (Gardnerella) vaginalis bacteria.
How do you make sulfathiazole?
Add 16 parts of anhydrous wool fat, 78 parts of white petrolatum and 1 part of sodium chloride dissolved in 4 parts of water. Use a water bath to melt the first four ingredients and then add water, stirring constantly. Heat the first three items to 140 F.
Which is the basic ring present in sulfadiazine?
Sulfadiazine is a sulfonamide consisting of pyrimidine with a 4-aminobenzenesulfonamido group at the 2-position. It has a role as an antimicrobial agent, an antiinfective agent, a coccidiostat, an antiprotozoal drug, an EC 2.5.
Is sulfathiazole acidic or basic?
Properties
| Property | Value | Source |
|---|---|---|
| pKa (Strongest Acidic) | 6.93 | ChemAxon |
| pKa (Strongest Basic) | 2.04 | ChemAxon |
| Physiological Charge | -1 | ChemAxon |
| Hydrogen Acceptor Count | 4 | ChemAxon |
Is Sulfathiazole toxic?
The toxic manifestations observed by Spink and Hansen2 in 100 patients with various infections and treated with sulfathiazole were: dermatitis (9), nausea and vomiting (6), nitrogen retention and oliguria (1), gross hematuria (1), drug fever (2), burning and itching of the eyes (2), injection of the conjunctivas (1) …
How do you use Sulfathiazole powder?
of sulfathiazole powder is instilled deep into the vaginal tract and spread down into the posterior fornix and about the cervix with the index and middle fingers. This maneuver has the additional advantage of being a final check for any sponge previously overlooked.
Is sulfathiazole toxic?
How do you use sulfathiazole powder?
Is Sulfathiazole polar?
Sulfathiazole is a white crystalline powder….3.1Computed Properties.
| Property Name | Property Value | Reference |
|---|---|---|
| Topological Polar Surface Area | 122 Ų | Computed by Cactvs 3.4.8.18 (PubChem release 2021.05.07) |
Which is long acting sulfonamide?
Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections….Long-Acting Antibacterial Sulfonamides.
| Drug | Target | Type |
|---|---|---|
| Sulfamerazine | Dihydropteroate synthase | target |
| Sulfamerazine | Serum albumin | carrier |
| Sulfadimethoxine | Cytochrome P450 2C9 | enzyme |
| Sulfameter | Dihydropteroate synthase | target |
Is sulfathiazole poisonous?