What is an aromatase inhibitor drug?

What is an aromatase inhibitor drug?

What are aromatase inhibitors? Aromatase inhibitors (AIs) lower estrogen levels by stopping an enzyme in fat tissue (called aromatase) from changing other hormones into estrogen. (Estrogen can fuel the growth of breast cancer cells.) These drugs don’t stop the ovaries from making estrogen.

What are examples of aromatase inhibitors?

There are three aromatase inhibitors:

• Arimidex (chemical name: anastrozole)
• Aromasin (chemical name: exemestane)
• Femara (chemical name: letrozole)

Do all aromatase inhibitors cause joint pain?

While aromatase inhibitors are very effective, they have potential side effects. Studies have found that anywhere from 25% to 50% of women who take the drugs experience joint pain or muscle pain.

What does an estrogen blocker do?

A substance that keeps cells from making or using estrogen (a hormone that plays a role in female sex characteristics, the menstrual cycle, and pregnancy). Estrogen blockers may stop some cancer cells from growing and are used to prevent and treat breast cancer.

What foods are natural estrogen blockers?

The following foods may lower levels of estrogen:

• Soy products. Products made from soy are uniquely rich in compounds called phytoestrogens.
• Cruciferous vegetables. Cruciferous vegetables contain a chemical called indole-3-carbinol, a chemical that may have anti-estrogen effects.
• Mushrooms.
• Curcumin and turmeric.

How to cope with side effects of aromatase inhibitors?

Hormonal therapies such as the aromatase inhibitor anastrozole can increase coughing. Try to drink at least 8 glasses of fluid a day to keep the lining of your breathing tube moist. Use a humidifier to increase the moisture in the air.

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What is aromatase therapy?

Aromatase inhibitors (AIs) are drugs used in hormonal therapy to prevent aromatase — an enzyme in fat tissue — from transforming hormones into estrogen. This medication does not prevent the ovaries from creating estrogen. Instead, AIs help to slow down the process and lower estrogen levels in ovaries that are no longer producing the hormone.