What is the drug precedex used for?
Dexmedetomidine is a sedative that is used to sedate a patient who is under intensive medical care and needs a mechanical ventilator (breathing machine).
Why is precedex used in ICU?
Background. Dexmedetomidine produces sedation while maintaining a degree of arousability and may reduce the duration of mechanical ventilation and delirium among patients in the intensive care unit (ICU).
How do you give a precedex infusion?
To prepare the infusion, withdraw 2 mL of Precedex Injection Concentrate, and add to 48 mL of 0.9% sodium chloride injection to a total of 50 mL. Shake gently to mix well.
How much does a vial of precedex cost?
The cost for Precedex intravenous solution (4 mcg/mL-NaCl 0.9%) is around $37 for a supply of 20 milliliters, depending on the pharmacy you visit….Intravenous Solution.
| Quantity | Per unit | Price |
|---|---|---|
| 20 milliliters | $1.85 | $36.91 |
| 1000 (10 x 100 milliliters) | $0.89 – $0.97 | $886.46 – $974.16 |
Is precedex better than propofol?
Conclusions: For ICU patient sedation, dexmedetomidine may offer advantages over propofol in terms of decrease in the length of ICU stay and the risk of delirium. However, transient hypertension may occur when dexmedetomidine is administered with a loading dose or at high infusion rates.
How does precedex make you feel?
The most common adverse reactions to dexmedetomidine are hypertension, hypotension, nausea, bradycardia, hypoxia, and anemia. 1 Overdoses of dexmedetomidine can lead to second- and third-degree heart block, which generally resolves spontaneously.
Does precedex affect heart rate?
Patients who receive dexmedetomidine and develop a greater than 30% decrease in heart rate may be at high risk for severe bradycardia leading to pulseless electrical activity. We urge caution when using dexmedetomidine, especially in patients with significant cardiac disease.
Can nurses give precedex?
Registered nurses must complete a moderate sedation inservice and maintain yearly competency. Sedation nurses may then administer midazolam, Fentanyl, Demerol and morphine, under the physician’s direction.
How much does a bottle of propofol cost?
Table 2Cost comparison of ICU sedatives a
| Group | Drug / Comparator | Price ($) |
|---|---|---|
| Selective α2 adrenergic agonist | Dexmedetomidine HCL | $45.2 / vial |
| Benzodiazepines | Midazolam | $5.8 / vial $126.3 / vial |
| Lorazepam | $12.42 / vial | |
| Propofol | $9.2 / vial $23.0 / vial $46.0/ vial |
Why is Precedex bad?
Because Precedex decreases sympathetic nervous system activity, hypotension and/or bradycardia may be expected to be more pronounced in patients with hypovolemia, diabetes mellitus, or chronic hypertension and in elderly patients.
Can propofol and Precedex be taken together?
Interactions between your drugs Using propofol together with dexmedetomidine may have increased effects on breathing, heart rate, blood pressure, and sedation. You will be monitored closely by your surgical team during anesthesia, and the doses of each medication adjusted accordingly.
What are the different sizes of Precedex injections?
Precedex (dexmedetomidine hydrochloride in 0.9% Sodium Chloride) injection is available as 80 mcg/20 mL (4 mcg/mL), 200 mcg/50 mL (4 mcg/mL) and 400 mcg/100 mL (4 mcg/mL) in 20 mL clear glass vials, 50 mL and 100 mL clear glass bottles, respectively.
How much dexmedetomidine is in a vial of predex?
Precedex Injection, 200 mcg dexmedetomidine/2 mL (100 mcg/mL) in a glass vial. To be used after dilution. Precedex Injection, 80 mcg dexmedetomidine/20 mL (4 mcg/mL) in a glass vial.
What is Precedex used to administer?
Precedex is a relatively selective alpha2-adrenergic agonist indicated for: Sedation of initially intubated and mechanically ventilated patients during treatment in an intensive care setting. Administer Precedex by continuous infusion not to exceed 24 hours. (1.1)
How much sodium chloride do you put in Precedex?
Precedex Injection, 200 mcg/2 mL (100 mcg/mL) Preparation of solutions is the same, whether for the loading dose or maintenance infusion. To prepare the infusion, withdraw 2 mL of Precedex Injection, and add to 48 mL of 0.9% sodium chloride injection to a total of 50 mL. Shake gently to mix well.