What happens after molar pregnancy removal?
After a molar pregnancy has been removed, molar tissue may remain and continue to grow. This is called persistent gestational trophoblastic neoplasia (GTN). This occurs in about 15% to 20% of complete molar pregnancies, and up to 5% of partial molar pregnancies.
Is invasive mole malignant?
The invasive mole is the malignant counterpart to the partial and complete hydatiform moles previously described. This entity is defined by the capacity to invade beyond the endometrial layer of the uterus where a normal pregnancy resides.
What is the difference between GTD and GTN?
For the purposes of discussion GTD is the appropriate collective name for hydatidiform mole, whereas the term gestational trophoblastic neoplasia (GTN) is reserved for cases with persistent human chorionic gonadotropin (hCG) titer elevation after evacuation of hydatidiform mole, metastatic disease, or choriocarcinoma.
What is treatment for choriocarcinoma?
Doctors typically treat gestational choriocarcinoma with chemotherapy. It works by either killing the cancerous cells or stopping the tumor from growing. Some people might need more than one type of chemotherapy. If the tumor has spread, the person might also need radiation therapy and surgery.
What is the difference between invasive mole and choriocarcinoma?
Invasive mole is unlike choriocarcinoma, the latter is without the presence of chorionic villi. It is important to distinguish between invasive mole and choriocarcinoma, as the former has a more favorable outcome.
Is invasive mole curable?
Invasive mole is curable with chemotherapy but hysterectomy decreases the need for multiple courses of chemotherapy and in patients with heavy bleeding or sepsis for control of complication and stabilization, chemotherapy is needed (6, 11).
How is GTD detected?
Ultrasound (sonogram) Ultrasound3 can identify most cases of GTD that are in the uterus, and will likely be one of the first tests done if your doctor suspects there may be a problem. To diagnose GTD, a different type of ultrasound called transvaginal ultrasonography is most often used.
How quickly does choriocarcinoma spread?
Choriocarcinoma can develop some months or even years after pregnancy and can be difficult to diagnose, because it is so unexpected. They can grow quickly and might cause symptoms within a short period of time. They can spread to other parts of the body but are very likely to be cured by chemotherapy treatment.
How long can you live with choriocarcinoma?
The complete remission rate and 5-year overall survival rate of postterm choriocarcinoma patients in our cohorts were 87.9 and 86.7 %, respectively. A history of resistance to multiagent chemotherapy, liver metastasis and a FIGO score greater than 12 were shown to be independent risk factors of prognosis.