Can mercaptopurine cause skin problems?
Sixteen episodes of a distinctive, papular rash occurred in eight patients following withdrawal of 6-mercaptopurine (6MP) and methotrexate (MTX) used as maintenance therapy for acute lymphoblastic leukemia (ALL). The rash also developed in one of the eight patients when only 6MP was discontinued.
Does mercaptopurine cause photosensitivity?
Drug fever has been reported with mercaptopurine. Additional adverse reactions that have been reported in patients who have received mercaptopurine include photosensitivity, hypoglycemia, and portal hypertension.
What are the side effects of 6-mercaptopurine?
6-MERCAPTOPURINE (6-MP)
- This medication belongs to a class of drugs called immunomodulators.
- Infrequently reported side effects may include headache, nausea, vomiting, diarrhea, tiredness, mouth sores, rash, fever, joint pain, low blood counts and anemia, and liver inflammation.
What happens when you stop taking mercaptopurine?
While you are being treated with mercaptopurine, and after you stop treatment with it, do not have any immunizations (vaccines) without your doctor’s approval. Mercaptopurine may lower your body’s resistance and the vaccine may not work as well or you might get the infection the vaccine is meant to prevent.
Does mercaptopurine cause weight gain?
Swelling of the body, tiredness, bruising. High blood pressure which may cause headaches, dizziness, blurred vision. Belly pain. Increased appetite and weight gain.
What does photosensitivity feel like?
Symptoms of photosensitivity vary from mild to severe. The most common symptom is an exaggerated skin rash or sunburn. Rashes may or may not cause itching. In some cases, a sunburn can be so severe that blistering develops.
How common is hair loss with mercaptopurine?
Side effects included leukopenia (11.2%), abnormal liver function tests (3.8%), various infections, including pneumonia (3.1%), pancreatitis (2.5%), nausea (2.1%), headache (2.8%), fever (1.4%), hair loss (1%), and rash (0.7%).
Does mercaptopurine make you gain weight?
Is 6 mercaptopurine an immunosuppressant?
6-mercaptopurine and its prodrug azathioprine (thiopurines) are immunosuppressant medications that have shown benefit in the maintenance of remission in both CD and UC. These drugs do not induce remission and can take up to 3 months to have their full effect.
Can you drink alcohol on mercaptopurine?
Yes, it safe to drink alcohol while you are taking mercaptopurine, however large quantities of alcohol should be avoided.
What is a sun rash called?
Answer From Lawrence E. Gibson, M.D. Sun rash and sun allergy are terms often used to describe a number of conditions in which an itchy red rash occurs on skin that’s been exposed to sunlight. A common form of sun rash is polymorphic light eruption, also known as sun poisoning.
Can a sunburn rash spread further?
If you go out in the sun and expose yourself to more UV rays before the rash has completely healed, then yes, it can spread further. It can be an allergy to the sun or a symptom of sun poisoning.
Why do I have a rash on my face after sunlight?
The rashcan be provoked by as little as 30 seconds exposure to daylight, with reactions to UVB, UVA and in severe cases to visible light. In some cases it is preceded by contact allergy(especially to plants such as chrysanthemum ) or contact photoallergyor photosensitivity reaction to a drug (when it is also called persistentlight reaction).
Is a sun rash hereditary?
Some people have a hereditary type of sun rash, while others develop signs and symptoms only when triggered by another factor — such as certain types of medications or skin exposure to certain plants, such as limes or wild parsnip.