What is the function of Diminazene?
Diminazene (INN; also known as diminazen) is an anti-infective medication for animals that is sold under a variety of brand names. It is effective against certain protozoa such as Babesia, Trypanosoma, and Cytauxzoon. The drug may also be effective against certain bacteria including Brucella and Streptococcus.
What is Diminazene diaceturate used for?
Diminazene aceturate is administered parenterally, primarily to dogs, for treatment of babesiosis, African trypanosomiasis, and, most recently, infections with Rangelia vitalii, a novel protozoal pathogen of dogs from Brazil.
What is the use of Berenil?
Diminazene aceturate (Berenil) has been widely used as a chemotherapeutic agent for trypanosomiasis in livestock since 1955. As in livestock, treatment of infected highly susceptible BALB/c mice with Berenil leads to rapid control of parasitemia and survival from an otherwise lethal infection.
What is Imidocarb dipropionate?
Imidocarb dipropionate (brand name Imizol®) is a drug used to treat infections caused by protozoa (single-celled organisms that sometimes cause disease). For example, it is used to treat the infection babesiosis in dogs. This infection is caused by the protozoa Babesia which is transferred to pets from tick bites.
Is Diminazene Aceturate safe in pregnancy?
Conclusion Although the pregnant rats showed no overt signs of systemic toxicity even at the highest dose of 21 mg/kg body weight diminazene aceturate in this study, it was concluded that the use of high doses of diminazene aceturate in an effort to combat resistant trypanosomes could have adverse reproductive effects …
What is trypanosomiasis in cattle?
African animal trypanosomiasis is a parasitic disease that causes serious economic losses in livestock from anemia, loss of condition and effects on reproduction. Losses in cattle are especially prominent. Animals other than livestock, including dogs, can also be affected.
How is trypanosomiasis prevented?
There is no vaccine or drug for prophylaxis against African trypanosomiasis. Preventive measures are aimed at minimizing contact with tsetse flies. Local residents in endemic countries are usually aware of the areas that are heavily infested and may be able to provide advice about places to avoid.
How is trypanosomiasis treated in cattle?
If detected early, Trypanosomosis can be treated with trypanocidal drugs for therapeutic and prophylactic purposes. Therapeutic drugs for cattle include diminazene aceturate, homidium chloride and homidium bromide. Prophylactic drugs for cattle include homidium chloride, homidium bromide and isometamidium.
What is the treatment for anaplasmosis in cattle?
Anaplasmosis in cattle is commonly treated with tetracycline antibiotics (tetracycline, chlortetracycline, oxytetracyline), which are most effective in the early stages of the disease. Clearance of carrier animals through antibiotic treatment has been reported but requires multiple doses over long periods.