What is the purpose of withanolides?
Withanolides is a series of small molecules widely found in Solanaceae. The solanaceae plant is traditionally used to treat asthma, parasitic disease, constipation, edema, glaucoma, headache, hepatopathy, reducing swelling and inflammation, postpartum pain, skin diseases [2-4].
What contains withanolides?
Withanolides are mainly distributed in various genera of Solanaceae, which includes Acnistus, Aureliana, Brachistus, Browallia, Datura, Deprea, Discopodium, Dunalia, Exodeconus, Hyoscyamus, Iochroma, Jaborosa, Larnax, Lycium, Mandragora, Nicandra, Physalis, Salpichroa, Saracha, Solanum, Trechonaetes, Tubocapsicum.
What are withanolide glycosides?
Withanolides are a group of at least 300 naturally occurring steroids built on an ergostane skeleton. They occur as secondary metabolites primarily in genera of the Nightshade family, for example in the tomatillo.
Does all ashwagandha have Withanolides?
Our Ashwagandha extract contains an unprecedented 10% withanolides, the main compound that gives ashwagandha its bioactive properties. Most other ashwagandha products consist of non-concentrated ashwagandha powder, and contain less than 2.5% withanolides!
Is all KSM-66 the same?
Sensoril Ashwagandha uses extracts from both the leaf and roots of the ashwagandha herb, while KSM-66 takes the more traditional route and comprises only the root extract. As a result, KSM-66 offers the highest concentration full spectrum extract.
Does all ashwagandha have withanolides?
Who can use ashwagandha?
Ashwagandha is an ancient medicinal herb with multiple health benefits. It can reduce anxiety and stress, help fight depression, boost fertility and testosterone in men, and even boost brain function. Supplementing with ashwagandha may be an easy and effective way to improve your health and quality of life.
Is Withanolide a steroid?
Withanolide A (1098) is a steroid from Withania somnifera (Indian ginseng), a plant whose roots been used in traditional ayurvedic medicine to improve cognitive function in the elderly (41).
Can ashwagandha lower testosterone?
Studies have shown that supplementation with ashwagandha in men led to a significant increase in testosterone levels, improved sperm quality, and higher antioxidant levels.
What is KSM-66 quality?
KSM-66 is the highest concentration, most bioavailable full-spectrum root extract on the market today, retaining all the natural constituents of the herb in the original balance. KSM-66 has the highest percentage of withanolides of all branded root-only extracts available today.
What is the strongest ashwagandha?
KSM-66
With a concentration of 5% withanolides (ashwagandha’s beneficial compounds), KSM-66 is the highest concentration of root-only ashwagandha extract available on the market. Developed with over 14 years of research and evaluated in 22+ human clinical trials, KSM-66 is also the most well-studied.
Who makes KSM-66 ashwagandha?
Ixoreal Biomed
KSM-66 is an ashwagandha extract made by Ixoreal Biomed, created via a process that took 14 years of R&D to develop and refine.
What are withanolides made of?
Withanolide. Structurally, withanolides consist of a steroid backbone bound to a lactone or one of its derivatives; they are produced via oxidation of steroids. It remains unknown to what end withanolides are produced; they may act as a deterrent for feeding insect larvae and other herbivores. In the laboratory,…
What is the molecular weight of withanolide a?
Withanolide A PubChem CID 11294368 Structure Find Similar Structures Molecular Formula C28H38O6 Synonyms withanolide A 32911-62-9 UNII-V903234S8G Molecular Weight 470.6
Where are withanolides found in plants?
They occur as secondary metabolites primarily in genera of the Nightshade family, for example in the tomatillo . Structurally, withanolides consist of a steroid backbone bound to a lactone or one of its derivatives; they are produced via oxidation of steroids.
What are ashwagandha’s withanolides?
Ashwagandha’s withanolides have been researched in a variety of animal studies examining their effect on numerous conditions, including immune function and even cancer ( Grandhi et al., 1994 ). Chemical analysis of Ashwagandha shows its main constituents to be alkaloids and steroidal lactones.