How does clindamycin affect the kidneys?
Clindamycin is extensively metabolized in the liver, most likely by the cytochrome P450 isoenzyme 3A4, but 10% of the drug is excreted by the kidney. A high urine concentration of clindamycin may precipitate in the renal tubular lumen and lead to tubular obstruction.
Is clindamycin good for urinary tract infection?
Clindamycin For Urinary Tract infection Clindamycin is effective against gram-positive anaerobic bacteria; therefore it is not effective against Escherichia coli and is not prescribed for UTIs. There are many other antibiotics that effectively treat UTIs.
What bacteria does clindamycin treat?
Clindamycin is an antibiotic used for treating serious infections. It is effective again several types of bacteria such as Staphylococcus aureus, Streptococcus pneumoniae, Staphylococcus epidermidis, and Propionibacterium acnes.
What is Clindahexal 150 mg used for?
Clindamycin is used to treat certain types of bacterial infections, including infections of the lungs, skin, blood, female reproductive organs, and internal organs. Clindamycin is in a class of medications called lincomycin antibiotics. It works by slowing or stopping the growth of bacteria.
Is clindamycin narrow spectrum?
Introduction. Clindamycin is a broad spectrum antibiotic used orally, topically and parenterally for bacterial infections due to sensitive organisms. Clindamycin has been linked to rare instances of acute liver injury.
Can clindamycin cause kidney failure?
Clindamycin: an unusual cause of acute kidney injury. It has been used with some well-known documented side effects such as gastrointestinal distress, drug fever, eosinophilia, erythema multiform and urticaria; however, AKI has rarely been reported as a side effect.
Can people with kidney disease take clindamycin?
In patients with mild to moderate impairment of renal function no dosage adjustment of clindamycin is necessary. However, in those with severe renal failure some modification to dosage would be prudent and this should be monitored by measuring serum levels of the antibiotic.
Can Clindamycin cause blood in urine?
Due to clindamycin achieving high concentration in the urine, it might precipitate and lead to tubular obstruction and consequent injury and hematuria [11].
What is Clindahexal 150mg used for?
Can I sleep after taking antibiotics?
Not only can antibiotics make you sleepy, but there are many other potential side effects of antibiotics. There is a long list of serious side effects for each medication.
What are the side effects of clindamycin clindahexal?
Clindahexal: Antibiotic. May cause heart burn. Severe and persistent diarrhea has been reported during or after treatment with clindamycin. This diarrhoea has been associated with blood and mucous in the stools and has sometimes resulted in acute colitis, this is rare.
What is clindahexal used to treat?
Clindamycin Hydrochloride: Clindahexal (Clindamycin Hydrochloride) phosphate and tretinoin gel 1.2% / 0.025% is indicated for the topical treatment of acne vulgaris in patients 12 years or older.
How does clindamycin work to kill bacteria?
How it works. Clindamycin works by inhibiting bacterial protein synthesis, which inhibits bacterial growth. Clindamycin has a bacteriostatic effect (stops bacteria from reproducing, but doesn’t necessarily kill them). Clindamycin belongs to the class of antibiotics known as lincosamide or lincomycin antibiotics.
Can you take clindamycin if you have diarrhea?
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop using clindamycin and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.