What is the best statin with the least side effects?
In the analysis of 135 previous studies, which included nearly 250,000 people combined, researchers found that the drugs simvastatin (Zocor) and pravastatin (Pravachol) had the fewest side effects in this class of medications. They also found that lower doses produced fewer side effects in general.
Which statins are the most effective?
Our data indicate that atorvastatin was the most effective statin tested in lowering cholesterol in LDL, non-HDL, and RLP in the fasting and fed states, and getting patients with CHD to established goals, with fluvastatin, pravastatin, lovastatin, and simvastatin having about 33%, 50%, 60%, and 85% of the efficacy of …
How do I choose the right statin?
The guidelines also help doctors choose the right statin at the right dose. For example, someone with a history of heart disease may need a high-intensity statin such as atorvastatin (Lipitor), while someone with a lower risk could take a low-intensity statin, such as pravastatin (Pravachol).
Are all statins equally effective?
15, 2011— — Two top-selling statins, Lipitor and Crestor, are equally effective in treating coronary artery disease, a new study found. Both drugs lower levels of LDL cholesterol — the bad cholesterol that can cause a build-up of blood-blocking plaque inside the arteries.
Is atorvastatin or simvastatin better?
Is atorvastatin or simvastatin better? Atorvastatin and simvastatin are both effective statin drugs for lowering blood cholesterol. However, atorvastatin is considered a more potent statin. Atorvastatin lasts longer in the body and can be taken in the morning or at night.
Is 40 mg of Lipitor a lot?
Adults—At first, 10 or 20 milligrams (mg) once a day. Some patients may need to start at 40 mg per day. Your doctor may increase your dose as needed. However, the dose is usually not more than 80 mg per day.
What are the side effects of statin therapy?
The most common statin side effects include: Headache. Difficulty sleeping. Flushing of the skin. Muscle aches, tenderness, or weakness (myalgia) Drowsiness. Dizziness. Nausea or vomiting.
What is a high dose for statin?
High-dose statins included rosuvastatin (Crestor) at doses of 10 milligrams (mg) or higher, atorvastatin (Lipitor) at doses of 20 mg or higher and simvastatin (Zocor) at doses of 40 mg. All other statin doses were considered low dose.
What is moderate high intensity statin?
High-Intensity Statin Therapy Offers Survival Benefit Over Moderate-Intensity Statins in CVD Patients. Treatment with a high-intensity statin, which includes rosuvastatin 20 or 40 mg and atorvastatin 40 or 80 mg, was associated with a 9% reduction in the risk of death at 1 year compared with taking a moderate-intensity statin.
How much does a statin cost?
This simvastatin price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies. The cost for simvastatin oral tablet 5 mg is around $9 for a supply of 30 tablets, depending on the pharmacy you visit.