What is Multifocality and Multicentricity?
The presence of two or more foci of cancer within the same breast quadrant is defined as multifocal, while the presence of two or more foci of cancer in different quadrants of the same breast is defined as multicentric.
What is tumor Multifocality?
Multifocal tumors are not multiple tumors; they originate from a unique cellular clone and grow multifocally in a single organ (liver, kidney, thyroid, etc.). These tumors are not included as multiple primary malignancies (MPM), but they can represent a single event of this syndrome.
What is tumor Multicentricity?
Multicentric: Having more than one center. A term often applied to tumors. A minority of Wilms tumors are multicentric and appear to represent separate tumors. A multicentric breast cancer involves two or more distinct primary tumors, usually in different quadrants of the breast. Also called multifocal or polycentric.
Which breast cancer is multicentric and bilateral?
Multiple breast cancers may present with different clinical and biological characteristics. The data indicate that multifocal (MF), multicentric (MC), and bilateral synchronous (BS) breast cancers (BC) are more aggressive and have an equivalent or moderately poorer survival rate compared with unilateral cases.
What is considered breast conserving surgery?
Breast-conserving surgery (BCS) removes the cancer while leaving as much normal breast as possible. Usually, some surrounding healthy tissue and lymph nodes also are removed.
What is a satellite nodule?
Satellite nodules are defined as well-circumscribed. accessory malignant foci clearly separated from the main tumor with identical histologic characteristics [1]; the presence of satellite nodules is predictive of poor prognosis in certain malignancies such as breast cancer [2] and melanoma [3].
What does tumor Focality mean?
This refers to the number of areas in which the cancer can be found (focality); unifocal being one tumor, multifocal being more than one tumor that originated from the same original tumor and multicentric being more than one tumor separated by normal breast tissue.
What does multifocal mean in medical terms?
Medical Definition of multifocal 1 : having more than one focal length multifocal lenses. 2 : arising from or occurring in more than one focus or location multifocal seizures.
What is multifocal glioblastoma?
Multifocal glioblastomas are tumors which have multiple discrete areas of contrast-enhancing tumor embedded with, or connected by, T2/FLAIR signal abnormality. Multifocal glioblastomas are considered to be part of the one tumor and are commonly encountered, accounting for 2-20% of all glioblastomas 3,4.
What is the difference between multifocal and multicentric breast cancer?
Breast cancers are defined as multifocal when there is more than one distinct tumour within the same quadrant of the breast (MF) and multicentric when multiple cancers develop in different quadrants of the breast (MC) [5].
What is multifocality in breast cancer?
Multifocality or multicentricity in breast cancer may be defined as the presence of two or more tumor foci within a single quadrant of the breast or within different quadrants of the same breast, respectively.
What is multicentric and multocal breast cancer?
Multicentric and multifocal breast cancer were defined as the presence of 2 or more invasive tumor foci within the different quadrants of the same breast or within a same quadrant of the breast, respectively. M/M and other prognostic factors were evaluated using univariate and multivariate analyses.
What does multifocality mean in medicine?
multifocality Multicentricity The simultaneous presence of a lesion–usually understood to be either an infection or a malignancy, in multiple sites McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc. Want to thank TFD for its existence?
Does tumor size predict tumor behavior in multifocal and multicentric breast cancer?
This study compares two methods of tumor size assessment to predict tumor behavior in the relationship between size and axillary node involvement for patients with multifocal and multicentric breast cancer. Methods