How is Linitis Plastica diagnosed?
Linitis plastica can be diagnosed by EUS-guided FNA following negative endoscopic biopsies.
What is Linitis Plastica?
Linitis plastica is a type of adenocarcinoma. Adenocarcinoma is the most common form of stomach cancer. Linitis plastica spreads to the muscles of the stomach wall and makes it thicker and more rigid.
How long can you live with Linitis Plastica?
Patients with linitis plastica of the stomach, have a poor prognosis with a five year survival of 3-10% in various studies [1,2]. Having this detrimental prognosis in mind, controversy in treatment of these patients still exists.
Is Linitis Plastica genetic?
What causes HDGC? HDGC is an inherited genetic condition that is rare. This means that the cancer risk and other features of HDGC can be passed from generation to generation in a family.
What is Borrmann classification?
Borrmann classification remains the most widely used and divides gastric carcinomas into four distinct types: polypoid carcinoma (type I), fungating carcinoma (type II), ulcerated carcinoma (type III), and diffusely infiltrative carcinoma (type IV, Figure 5).
Is Linitis Plastica curable?
In conclusion, gastric linitis plastica is one of the forms of adenocarcinoma which usually presents at a later stage, where curative treatment is not an option for the majority of cases. The prognosis may be ameliorated with complete resection. Surgery should only be offered where complete resection is anticipated.
Is Linitis Plastica hereditary?
How common is CDH1?
Among families that fit these conditions, about 25% to 40% will have a CDH1 gene mutation. Families with multiple cases of diffuse stomach cancer, as well as patients diagnosed with diffuse stomach cancer before age 40, are referred for genetic counseling and testing for CDH1 gene mutations.
What is surgical removal of stomach?
Surgery to remove your stomach is called a gastrectomy. There are different types of gastrectomy.