How do you calculate tubular reabsorption?
Tubular Reabsorption of Phosphate Equation Page :: MediCalculator ::: ScyMed ::: *Also, TRP = (1 – (FEPi/100)) x 100. FEPi < 10% (< 0.1 fraction) = low. FEPi > 20% (> 0.2 fraction) = high.
What is a normal tubular reabsorption of phosphate?
The normal range of tubular reabsorption of phosphorus (TRP) is 78–91% and a value above 95% is a significant marker showing insufficient P supplement (10).
How do you calculate fractional excretion of phosphate?
The fractional excretion of phosphate (FeP) was calculated using the following formula: FeP = (24-h urine phosphate × serum creatinine) × 100/(serum phosphate X 24-h urine creatinine).
How do you calculate GFR TmP?
TmP/GFR = ratio of tubular maximum reabsorption rate of phosphate to glomerular filtration rate. Phosphate flow TmP/GFR decreases when plasma phosphate is increased by an increase in the rate of phosphate flow into the extracellular space from gut, cells or bone, and increases when flow is decreased.
What is tubular reabsorption test?
Clinical Information The tubular reabsorption of phosphate (TRP) is the fraction (or percent) of filtered phosphorus that is reabsorbed by renal tubules. Its measurement is useful when evaluating patients with hypophosphatemia.
What happens in tubular reabsorption?
Tubular reabsorption is the process that moves solutes and water out of the filtrate and back into your bloodstream. This process is known as reabsorption, because this is the second time they have been absorbed; the first time being when they were absorbed into the bloodstream from the digestive tract after a meal.
What is a TRP test?
TRP (Tubular Reabsorption of Phosphorus) Test Code: NEOTRP. Tests performed include serum and urine phosphorus, serum and urine creatinine plus a calculation for percent tubular reabsorption of phosphorus.
When should phosphate be corrected?
Once serum phosphate levels reach 1.5 md/dL, therapy should be switched to oral replacement. The intracellular nature of phosphate makes interpreting a low serum phosphate level difficult and predicting the amount required to replenish cellular stores nearly impossible.
How do you calculate phosphate replacement?
The dose was calculated according to the following equation: Phosphate dose in mmol=0.5×Body Weight×(1.25-[serum Phosphate]). Phosphate levels were measured immediately upon completion of the infusion, as well as the next morning at 8 am. Results: Post-infusion phosphate levels were >0.6 mmol/L in 98% of the patients.
What is tubular load?
Tubular load (Tubular load (TTLL )) Tubular load of a substance is the total amount of that substance present in the filtrate produced by all nephrons of both kidneys per minute Primarily depends on GFR. 44.
What is the formula for fractional tubular reabsorption of phosphate?
Subtract this fraction from 1.0 to give the fractional tubular reabsorption of phosphate (TRP). TRP = 1 – serum creatinine x Urine phosphate Urine creatinine x Serum phosphate 3.
What is TRP in renal tubular reabsorption?
Fractional Tubular Reabsorption of Phosphate (TRP) The fraction of phosphate in the glomerular filtrate that is reabsorbed in the renal tubules. If TRP is low in hypophosphataemia this usually points to a renal tubule defect. Indications
How do you calculate TMP GFR from serum phosphate?
TmP/GFR = a x serum phosphate, where = 0.3 x TRP. 1- (0.8 x TRP) Alternatively, TmP/GFR can also be determined using a nomogram after measuring fasting plasma and urine concentrations of phosphate and creatinine.
How do you test for phosphate clearance in urine?
Procedure Overnight fast The first voided urine should be discarded. Collect a 25 ml sample of the second void urine into a universal container for urine creatinine and phosphate Send with serum electrolytes and phosphate. Calculation Calculate the ratio of phosphate clearance to creatinine clearance (CP/CCr)