What is MDMB-CHMICA (MMB-CHMINACA)?
MDMB-CHMICA (also incorrectly known as MMB-CHMINACA) is an indole -based synthetic cannabinoid that is a potent agonist of the CB1 receptor and has been sold online as a designer drug. While MDMB-CHMICA was initially sold under the name “MMB-CHMINACA”, the compound corresponding to this code name (i.e.
How effective is mdmdmb-CHMICA as a CB 1 agonist?
MDMB-CHMICA acts as a highly potent full agonist of the CB 1 receptor with an efficacy of 94% and an EC 50 value of 0.14 nM, which is approximately 8 times lower than the EC 50 of JWH-018 (1.13 nM) and twofold lower than AB-CHMINACA (0.27 nM).
Is MDMB-CHMICA legal in the UK?
MDMB-CHMICA is illegal in Austria, Canada, China, Croatia, Denmark, Estonia, Finland, Germany, Greece, Hungary, Latvia, Lithuania, Louisiana, Luxembourg, Norway, Turkey, the UK, Sweden and Switzerland. In August 2016 the European Commission proposed a ban on MDMB-CHMICA across the European Union.
What are mdmdmb-CHMICA’s main metabolic reactions?
MDMB-CHMICA’s main metabolic reactions comprise mono-hydroxylations and hydrolysis of the carboxylic ester function.