What happened to Fruta Planta?
Reflecting these safety concerns, the ingredient was withdrawn from the US market in December 2010. Sold exclusively on the internet under the brand names Fruta Planta and Reduce Weight Fruta Planta, the US distributor is PRock Marketing LLC, of Kissimmee, Florida, which has recalled the products.
How effective is sibutramine?
At 1 year, adults receiving sibutramine, 10 to 15 mg/d, lost an average of 4.5 kg (9.8 pounds) more than adults receiving placebo. Adults taking sibutramine for 1 year are 19% to 34% more likely to achieve 5% weight loss and 12% to 31% more likely to achieve 10% weight loss than those taking placebo.
How long does sibutramine stay in your system?
Sibutramine is metabolized by cytochrome P450 isozyme CYP3A4 into two pharmacologically-active primary and secondary amines (called active metabolites 1 and 2) with half-lives of 14 and 16 hours, respectively. Peak plasma concentrations of active metabolites 1 and 2 are reached after three to four hours.
Is sibutramine safe for weight loss?
Sibutramine is safe and effective for weight loss in obese patients whose hypertension is well controlled with angiotensin-converting enzyme inhibitors.
What are the benefits of sibutramine?
Sibutramine affects chemicals in the brain that affect weight maintenance. Sibutramine is used together with diet and exercise to treat obesity that may be related to diabetes, high cholesterol, or high blood pressure. Sibutramine may also be used for other purposes not listed in this medication guide.
Who should not take sibutramine?
Do not use sibutramine if you have taken an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) in the last 14 days.
What are the side effects of sibutramine?
COMMON side effects
- a stuffy and runny nose.
- dry mouth.
- constipation.
- dizziness.
- difficulty sleeping.
- decreased appetite.
- headache.
- nervousness.