What site is Extralymphatic in lymphoma?
The most common extralymphatic sites were the gastrointestinal tract, the head and neck region, and the lung.
What are extranodal sites in lymphoma?
Extranodal lymphoma, by definition, involves sites other than lymph nodes, spleen, thymus and the pharyngeal lymphatic ring. Involvement of the spleen in HD is considered as nodal disease but in the case of non-Hodgkin lymphoma (NHL) the spleen is regarded as an extranodal site.
What is nodal lymphoma?
Nodal marginal zone lymphoma is a rare, slow-growing (indolent) B-cell non-Hodgkin lymphoma (NHL). It can change into a fast-growing (aggressive) type of NHL. Nodal marginal zone lymphoma usually only affects the lymph nodes.
What is an Extralymphatic organ?
Extralymphatic means other than lymph nodes and other lymphatic structures. These lymphatic structures include spleen, thymus gland, Waldeyer’s ring (tonsils), Peyer’s patches (ileum) and lymphoid nodules in the appendix. Any lymphatic structure is to be coded the same as a lymph node region.
Is extranodal lymphoma treatable?
A combined treatment with chemotherapy and RT is considered a valid therapeutic approach in patients with localized NHL, either nodal or extranodal, in most anatomic sites, including Waldeyer’s ring (100-102). However, the combinatory treatment is often associated with relevant acute and chronic toxicity (99,103).
What is extranodal and solid organ sites?
The term extranodal disease refers to lymphomatous infiltration of anatomic sites other than the lymph nodes. Almost any organ can be affected by lymphoma, with the most common extranodal sites of involvement being the stomach, spleen, Waldeyer ring, central nervous system, lung, bone, and skin.
Is spleen extranodal site?
The spleen is considered extranodal region in NHL and nodal organ in HD (1). Splenic involvement is more common in HD. Organ size is not a criterion for diagnosis as spleen can be normal in size with tumor infiltration or may be enlarged without lymphomatous involvement (2).