What is Mekinist used for?

What is Mekinist used for?

TAFINLAR and MEKINIST are prescription medicines that can be used in combination to treat a type of lung cancer called non-small cell lung cancer (NSCLC) that has spread to other parts of the body (metastatic NSCLC), and that has a certain type of abnormal “BRAF V600E” gene.

Does Mekinist cause high blood pressure?

Mekinist can cause new or worsening high blood pressure (hypertension). Your healthcare provider should check your blood pressure during treatment with Mekinist.

Is Mekinist FDA approved?

The U.S. Food and Drug Administration approved Tafinlar (dabrafenib) and Mekinist (trametinib), administered together, for the treatment of anaplastic thyroid cancer (ATC) that cannot be removed by surgery or has spread to other parts of the body (metastatic), and has a type of abnormal gene, BRAF V600E (BRAF V600E …

How is Tafinlar administered?

Administration. Take TAFINLAR at doses approximately 12 hours apart. Take TAFINLAR at least 1 hour before or 2 hours after a meal [see CLINICAL PHARMACOLOGY]. Do not take a missed dose of TAFINLAR within 6 hours of the next dose of TAFINLAR.

Is Mekinist chemotherapy?

Mekinist is the trade name for the generic chemotherapy drug trametinib. In some cases, health care professionals may use the generic name trametinib when referring to the trade name Mekinist. Drug type: Mekinist is a targeted therapy.

What is Trametinib approved for?

Trametinib, as a monotherapy, has been approved in the US for the treatment of unresectable or metastatic malignant melanoma with BRAF V600E or V600K mutations, as detected by an FDA-approved test.

When was Trametinib approved by the FDA?

FDA approves dabrafenib plus trametinib for adjuvant treatment of melanoma with BRAF V600E or V600K mutations. On April 30, 2018, the Food and Drug Administration granted regular approval to dabrafenib (TAFINLAR, Novartis Pharmaceuticals Corp.) and trametinib (MEKINIST, Novartis Pharmaceuticals Corp.)

Can you take Mekinist and Tafinlar together?

Mekinist should be taken the same time each day, preferably with either the morning or evening dose of Tafinlar. Both medications should be taken at least 1 hour before a meal or 2 hours after a meal.