What is the difference between amphotericin B and AmBisome?
These results suggest that AmBisome® is an effective and safe antifungal agent in the treatment of systemic candidiasis in VLBWI. The mean duration of AmBisome® therapy was shorter than amphotericin B therapy, but fungal eradication rates, eradication time, and mortality rates were similar.
What does fungizone treat?
Fungizone is a prescription medicine used to treat the symptoms of fungal infections, Cryptococcal Meningitis and Visceral Leishmaniasis. Fungizone may be used alone or with other medications. Fungizone belongs to a class of drugs called Antifungals, Systemic.
What is the difference between AmBisome and Abelcet?
Abelcet has comparable cost to Amphotec but generally better tolerated with less infusion related reactions. Abelcet has comparable cost to AmBisome, but resulted in a higher incidence of nephrotoxicity and infusion related side effects.
Who manufactures AmBisome?
AmBisome® is a registered trademark of Gilead Sciences, Inc.
What is AmBisome used for?
This medication is used to treat a variety of serious fungal infections. It is often used in patients who cannot tolerate or who do not respond to the regular amphotericin treatment. It works by stopping the growth of fungi.
How do you dilute AmBisome?
AmBisome must be diluted with 5% Dextrose Injection to a final concentration of 1 to 2 mg/mL prior to administration. Lower concentrations (0.2 to 0.5 mg/mL) may be appropriate for infants and small children to provide sufficient volume for infusion.
Is ambisome light sensitive?
AMPHOTERICIN 81 Clinical use of amphotericin B is associated with many problems, the least of which are concerned with the sensitivity of this drug to light. In fact, the package insert cautions the user to protect all solutions, including those prepared for infu- sion, from exposure to light.
How do you use fungizone?
Fungizone is injected into a vein through an IV. A healthcare provider will give you this injection. The medicine must be given slowly through an IV infusion, and can take from 2 to 6 hours to complete. Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Fungizone is injected.
What is the difference between amphotericin and liposomal amphotericin?
Using a composite end-point, the two drugs were equivalent in overall efficacy. However, the liposomal amphotericin B treatment group had fewer proven fungal infections, fewer infusion-related side effects and less nephrotoxicity.
Is AmBisome expensive?
The cost for AmBisome intravenous powder for injection 50 mg is around $289 for a supply of 1 powder for injection, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
Where is AmBisome manufactured?
Gilead will manufacture AmBisome at its San Dimas, California facility and receive royalty payments. In August 1997 the U.S. Food and Drug Administration (FDA) approved AmBisome for a broader range of treatment.