What is estriol used for?
Estriol is a weak estrogen used to treat vaginal dryness and estrogen deficiency conditions, such as vaginitis and vulvar itching. A hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen.
Does estriol cream stop hot flushes?
Conditions treated by estriol and estradiol Estradiol is FDA approved to treat symptoms of menopause. These symptoms include vasomotor symptoms such as hot flashes, night sweats, and flushing of the skin. Other menopausal symptoms include vaginal atrophy, or vaginal dryness, inflammation, and thinning.
Is estriol safe to use?
Although estriol appears to be much safer than estrone or estradiol, its continuous use in high doses may have a stimulatory effect on both breast and endometrial tissue. Therefore, it is advised to be used with caution in patients at risk for hormone-dependent cancers.
What are the side effects of estriol cream?
The following adverse reactions, associated with estrogen treatment may occur during estriol therapy or overdose: Nausea and vomiting, breast tenderness or pain in the breasts, vaginal bleeding or spotting during or on withdrawal of therapy, excessive production of cervical mucus, headache.
How long is it safe to use estriol cream?
In order to prevent endometrial stimulation, the daily dose should not exceed 1 application (0.5 mg estriol) nor should this maximum dose be used for longer than several weeks (maximum 4 weeks).
How long does it take for estriol cream to work?
Vaginal atrophy can be treated with topical estrogen including Estrace Vaginal Cream and it can take 3 to 4 weeks to reach its maximum effect. Atrophic vaginitis is an inflammation or irritation of the vagina caused by thinning and shrinking of the tissues of the vagina and decreased lubrication of the vaginal walls.
How quickly does estrogen cream work?
What happens if you use too much estrogen cream?
Overdosage of estrogen may cause nausea and vomiting, and withdrawal bleeding may occur in females. The usual dosage range of Estrace Vaginal Cream is 2 to 4 g (marked on the applicator) daily for one or two weeks, then gradually reduced to one half initial dosage for a similar period.
Does estrogen cream make you gain weight?
Topical, but not oral, estradiol prevents this increase in body fat and leptin. An interesting fact about visceral obesity is that women who take NO estrogen can also get weight gain around their middle because they develop insulin resistance.
A systematic review conducted in 2017 of intravaginal estriol cream found that the majority of adverse events reported included localized discomfort and mild breast pain. 2 Taking estriol may also decrease production of breast milk.
How do you apply estriol cream?
PDF Transcript. Fill the applicator up to the ring mark with Estriol cream to get the correct dose. If you are not sure if any of the above apply to you, talk to your doctor or pharmacist before using Estriol. You are more likely to get a blood clot if: Use the applicator to apply the cream in the vagina.
How do I use estriol cream to prevent blood clots?
You are more likely to get a blood clot if: Use the applicator to apply the cream in the vagina. A good time to do this is before going to bed. Before or after vaginal surgery Before surgery – the dose is 1 applicator up to the ring (0.5 mg estriol in 0.5 g of cream) a day for 2 weeks before the operation.
a medicine called estriol. It belongs to a group of medicines called Hormone Replacement Therapy (HRT). Before or after vaginal surgery to help wound healing. Do not use this medicine if any of the above apply to you. If Ovestin. Estriol (the medicine in Ovestin) is one of the natural oestrogens. 5. How to store Ovestin