What is acute stage Kawasaki disease?
The acute febrile phase usually lasts seven to 14 days. This phase, which ends with the resolution of fever, is characterized by conjunctival injection, mouth and lip changes, swelling and erythema of the hands and feet, rash and cervical lymphadenopathy (Figures 1,2 and 3).
What are the three phases of Kawasaki disease?
The clinical presentation of KD varies over time, with the clinical course conventionally divided into 3 stages: acute, subacute, and convalescent (see the image below). Some authors add a fourth, chronic, phase. Clinical manifestations and time course of Kawasaki disease.
Which of the following is a mainstay for the treatment of Kawasaki disease during the acute febrile phase?
During the acute phase, aspirin is given at anti-inflammatory doses of 80 to 100 mg/kg either until the patient has been afebrile for 48 hours or for 14 days.
What are possible serious sequelae complications of Kawasaki disease?
Long-term complications included stenosis, myocardial infarction, and death. Other series have reported both symptomatic and asymptomatic coronary artery occlusion in regions of previous aneurysms(22,23), coronary artery stenosis(24), coronary artery calcification(25), diastolic dysfunction(26), and sudden death(27).
Can you survive Kawasaki disease?
Children with Kawasaki disease might have high fever, swollen hands and feet with skin peeling, and red eyes and tongue. But Kawasaki disease is usually treatable, and most children recover without serious problems if they receive treatment within 10 days of onset.
How Long Can Kawasaki disease last?
With treatment, a child might start to improve soon after the first gamma globulin treatment. Without treatment, Kawasaki disease lasts about 12 days. However, heart complications might last longer.
What is the first line of treatment for Kawasaki disease?
First-line treatment for Kawasaki disease is IVIG in a dose of 2 g per kg of body weight in a single infusion. For treatment of Kawasaki disease, high-dose aspirin (80 to 100 mg per kg per day, divided into four doses) should be given with IVIG.
What treatment is used for Kawasaki disease?
Treatment includes intravenous gamma globulin (IVIG), which is an infusion through your child’s IV and high-dose aspirin every six hours. These medicines help reduce the swelling and inflammation in the blood vessels.
What happens after Kawasaki?
Long-term effects of Kawasaki disease, however, can include heart valve issues, abnormal heartbeat rhythm, inflammation of the heart muscle, and aneurysms (bulges in blood vessels). These lasting heart conditions are rare. Less than 2% of patients experience coronary artery enlargement that carries over into adulthood.
Can Kawasaki be fatal?
Aneurysms increase the risk of blood clots, which could lead to a heart attack or cause life-threatening internal bleeding. For a small percentage of children who develop coronary artery problems, Kawasaki disease can cause death.