What does a positive smooth muscle antibody mean?

What does a positive smooth muscle antibody mean?

If your results show a high amount of SMA antibodies, it probably means you have the type 1 form of autoimmune hepatitis. A lower amount may mean you have the type 2 form of the disease. If no SMAs were found, it means your liver symptoms are being caused by something different than autoimmune hepatitis.

What is the normal range for smooth muscle antibody test?

Titers generally range from 1:80-1:320 and persist for years. In viral hepatitis the titers are below 1:80 and are transient. Low titers (1:20 to 1:40) are found in approximately 50% of patients with primary biliary cirrhosis.

What is actin antibody in blood test?

Description. The actin (Smooth Muscle) antibody (ASMA) blood test detects if the smooth muscle antibody is in the blood and assists in the evaluation of the condition of a person with hepatitis. An ASMA test is useful to determine if the liver inflammation is autoimmune or not.

What is anti-smooth muscle IgG?

Anti-smooth muscle antibody is a blood test that detects the presence of antibodies against smooth muscle. The antibody is useful in making a diagnosis of autoimmune hepatitis. Blood is drawn from a vein (venipuncture), usually from the inside of the elbow or the back of the hand.

What is F actin IGG?

Actin (Smooth Muscle) Antibody (IgG) – Actin is the major antigen to which smooth muscle antibodies react in autoimmune hepatitis. F-Actin IGG antibodies are found in 52-85% of patients with Autoimmune Hepatitis (AIH) or chronic active hepatitis and in 22% of patients with Primary Biliary Cirrhosis (PBC).

What does positive actin antibody mean?

What does the test result mean? A significant increase in the blood titer of SMA or actin antibody and/or ANA is usually due to autoimmune hepatitis type 1. A small increase in SMA or actin antibody may be present in up to 50% of patients with primary biliary cholangitis (PBC).

What is F-actin IgG?

What can cause smooth muscle antibodies?

Anti-smooth muscle antibodies are found in autoimmune liver diseases such as primary biliary cholangitis and autoimmune hepatitis (AIH)….Autoimmune hepatitis

• enlarged liver, called hepatomegaly.
• abdominal distension, or swelling.
• tenderness over the liver.
• dark urine.
• pale-colored stools.

What is F actin IgG?

Can you live a normal life with autoimmune hepatitis?

Therefore, it is possible to have a normal life expectancy, even with the life-long condition of autoimmune hepatitis.

What are the anti smooth muscle antibodies?

Anti-smooth muscle antibody. Anti-smooth muscle antibody is a blood test that detects the presence of antibodies against smooth muscle. The antibody is useful in making a diagnosis of autoimmune hepatitis. Antibodies. An antibody is a protein produced by the body’s immune system when it detects harmful substances, called antigens.

What is smooth muscle AB titer?

Smooth muscle antibodies (SMA) are autoantibodies, proteins produced by the body’s immune system that recognize and attack its own actin, a protein found in smooth muscle and other tissues, especially the liver. This test detects and measures the amount ( titer) of SMA (or antibody against actin) in the blood.

What is smooth muscle test?

An anti-smooth muscle antibody (ASMA) test detects antibodies that attack smooth muscle. This test requires a blood sample. Your immune system detects substances called antigens that may be harmful to your body. Viruses and bacteria are covered with antigens.