How do you say methylenetetrahydrofolate?
Methylenetetrahydrofolate reductase Pronunciation. Methylenete·trahy·dro·fo·late re·duc·tase.
What does methylenetetrahydrofolate reductase do?
The MTHFR gene provides instructions for making an enzyme called methylenetetrahydrofolate reductase. This enzyme plays a role in processing amino acids, the building blocks of proteins. Methylenetetrahydrofolate reductase is important for a chemical reaction involving the vitamin folate (also called vitamin B9).
Is MTHFR autoimmune?
1 The MTHFR mutation is also believed to predispose a person to certain cancers, birth defects, and autoimmune diseases.
What happens if you have MTHFR and take folic acid?
Folic acid: Supplementation with folic acid may compensate for the reduced MTHFR enzyme activity, leading to normal levels of the active L-methylfolate, which may have an impact on depression response. Studies investigating the effect of folic acid supplementation on depression response have produced mixed results.
What foods to avoid if you have MTHFR?
People with MTHFR mutations may want to avoid foods that contain the synthetic form of folate, folic acid — though the evidence is not clear that’s necessary or beneficial. Be sure to check labels, as this vitamin is added to many enriched grains, like pasta, cereals, breads, and commercially produced flours.
Can you drink alcohol with MTHFR?
Conclusions: Moderate alcohol intake and low MTHFR activity have adverse effects on tHcy, but those effects may be overcome by sufficient folate intake.
Does MTHFR affect liver?
The methylenetetrahydrofolate reductase (MTHFR) genotypes 677CT and 677TT are associated with elevated serum homocysteine (Hcy) levels by means of lowering the activity of MTHFR, and the increase in serum Hcy may be linked to increased susceptibility to non-alcoholic fatty liver disease (NAFLD).