Can you have Ehlers Danlos and ankylosing spondylitis?
Research has shown hypermobility Ehlers–Danlos syndrome (hEDS) to be associated with some complicated rheumatologic disease. In this feature paper, the authors discuss the prevalence and pathophysiology of rheumatologic conditions, specifically ankylosing spondylitis and rheumatoid arthritis, in patients with hEDS.
Is Ehlers Danlos an autoimmune disease?
In the United States, two million people live with rheumatoid arthritis, and another 1.5 million live with lupus. A much rarer group of connective tissue disorders is called Ehlers-Danlos syndrome. Unlike the diseases noted above, Ehlers-Danlos syndrome is not an autoimmune condition, it’s an inherited disorder.
What gene is affected by Ehlers Danlos Syndrome?
Mutations in at least 20 genes have been found to cause the Ehlers-Danlos syndromes. Mutations in the COL5A1 or COL5A2 gene, or rarely in the COL1A1 gene, can cause the classical type.
Does Ehlers Danlos Syndrome affect the immune system?
People with Ehlers-Danlos Syndrome (EDSers) may have higher risk for infections. Fragile skin and poor healing may lead to skin infections. EDSers often have a lowered immune system, possibly due to chronic stress on multiple body systems or an IgG-3 deficiency.
Do Rheumatologists diagnose Ehlers Danlos?
The rheumatologist can play an important role in the diagnosis of EDS and is central to the ongoing management of many EDS patients.
What kind of doctor manages Ehlers Danlos?
Rheumatologists and EDS The Ehlers Danlos Syndromes are categorized as “connective tissue disorders,” and it is rheumatologists who are supposed to specialize in such conditions.
What is the life expectancy of someone with Ehlers Danlos Syndrome?
People affected by vascular EDS have a median life expectancy of 48 years and many will have a major event by age 40. The lifespan of people with the kyphoscoliosis form is also decreased, largely due to the vascular involvement and the potential for restrictive lung disease.
Can you donate blood if you have Ehlers Danlos Syndrome?
Certain medications may delay your ability to donate blood….Medical Conditions Affecting Donation.
| Medical Conditions | Eligibility |
|---|---|
| Ehlers Danlos Syndrome | Acceptable |
| Ehrlichiosis | Accept if asymptomatic and treatment completed |
Is Ehlers Danlos considered a disability?
Can I Get Disability For Ehlers-Danlos Syndrome (EDS)? The answer is that Ehlers-Danlos Syndrome (EDS) can be a disabling condition, depending on how it presents. EDS is a genetic disorder affecting connective tissues and causing an array of serious physical problems, ranging from joint pain to cardiovascular issues.
Who is most likely to get Ehlers Danlos Syndrome?
Most are rare e.g., 1 in 40,000 – 200,000 and some are ultrarare i.e., less than 1 in a million people. Individuals of all racial and ethnic backgrounds are affected by EDS which can present with complications from birth and progress over time.
What are the features of Ehlers Danlos syndrome?
Features shared by many types include joint hypermobility and soft, velvety skin that is highly elastic (stretchy) and bruises easily. Mutations in a variety of genes may lead to EDS; however, the underlying genetic cause in some families is unknown.
How do I get help with Ehlers-Danlos syndrome?
Please reach out to a GARD Information Specialist at 301-251-4925. Try our interactive tool for help finding information, services, experts, financial aid, and more! Ehlers-Danlos syndromes (EDS) are a group of inherited connective tissue disorders caused by abnormalities in the structure, production, and/or processing of collagen.
What is mymyopathic Ehlers Danlos syndrome?
Myopathic EDS (mEDS) characterized by congenital muscle hypotonia, and/or muscle atrophy, that improves with age, Proximal joint contractures (joints of the knee, hip and elbow); and hypermobility of distal joints (joints of the ankles, wrists, feet and hands).
What is the long-term outlook for people with Ehlers-Danlos syndrome (EDS)?
The long-term outlook ( prognosis) for people with Ehlers-Danlos syndromes (EDS) varies by subtype. The vascular type is typically the most severe form of EDS and is often associated with a shortened lifespan. People affected by vascular EDS have a median life expectancy of 48 years and many will have a major event by age 40.