What are drug-coated balloons used for?
Drug-Coated Balloon (DCB) angioplasty is similar to plain old balloon angioplasty procedurally, but there is the addition of an anti-proliferative medication coating the balloon, as well as an excipient to aid in drug transfer, which may help prevent restenosis.
What is a drug-eluting balloon?
Abstract. A drug-eluting balloon is a non-stent technology in which the effective homogenous delivery of anti-proliferative drugs is processed by the vessel wall through an inflated balloon.
What is a Wolverine Cutting Balloon?
The Wolverine Cutting Balloon Device is indicated for dilatation of stenoses in coronary arteries for the purpose of improving myocardial perfusion in those circumstances where a high pressure balloon resistant lesion is encountered.
How does a Cutting Balloon work?
When the Cutting Balloon is inflated, the tiny atherotomes score the arterial disease, interrupting the elastic and fibrotic continuity and allowing for plaque displacement, thereby decreasing the amount of trauma to the artery wall.
How long does a drug-eluting stent work?
If you get a drug-eluting stent, you will probably take both of these medicines for at least 6 months. If you get a bare-metal stent, you may take both medicines for at least 1 month. If you had a heart attack, you may take both medicines for at least 1 year.
What are drug-eluting stents coated with?
A drug-eluting stent is coated with time-release medicine. That medication is gradually released into your blood vessel to prevent it from becoming blocked again.
What drug is used in drug-eluting stents?
Paclitaxel-eluting or sirolimus-eluting stents to prevent restenosis in diabetic patients. N Engl J Med.
What is a scoring balloon?
The AngioSculpt percutaneous transluminal coronary angioplasty scoring balloon catheter is used for the treatment of coronary artery stenosis, including complex type C lesions and in-stent restenosis.
What size wires are usually utilized in coronary balloon angioplasty?
Balloon catheters are either over-the-wire (OTW) or rapid-exchange (RX). Most OTW and monorail balloons are compatible with 0.014 inch guide wires. OTW balloons require use of exchange length 300 cm wires.
How safe is balloon angioplasty?
Although angioplasty is normally safe, there is a small risk of serious complications, such as: Bleeding from the blood vessel where the catheter was placed. Damage to blood vessels from the catheter. An allergic reaction to the dye given during the angioplasty.
What is drug-coated Balloon (DCB)?
Drug-coated balloon (DCB) treatment is based on a leave-nothing-behind concept and therefore it is not limited by stent thrombosis and long-term DAPT; it directly delivers an anti-proliferative drug which is coated on a balloon after improving coronary blood flow.
What is the difference between drug-eluting and Drug-coated balloons?
Drug-coated balloons are designed to dilate the stenotic coronary artery while introducing medication to suppress neointimal hyperplasia. With a drug-eluting balloon, both the polymer and stent platform are absent; this completely
Are drug-coated balloons effective for peripheral artery disease?
The US FDA recently approved drug-coated balloons (DCBs) for symptomatic femoro-popliteal peripheral artery disease [123].
Are PEO/PTX coated balloons better for drug delivery?
An in vitro study showed that PEO/PTX coated balloons have better drug loading and release rate than balloons coated with other excipients such as shellac, iopromide, polysorbate/sorbitol, and urea ( Xiong et al., 2016 ). Some of the drug-eluting balloon systems that are currently clinically used include PACCOCATH, IN.