Can diol dehydratase dehydrate 1 2 ethanediol?

Can diol dehydratase dehydrate 1 2 ethanediol?

Diol dehydratase and glycerol dehydratase can also catalyze the dehydration of 1,2-ethanediol to acetaldehyde [37]. However, only marginal activity of diol dehydratase toward meso-2,3-butanediol dehydration has been observed.

How are aldehydes formed from diols?

Vicinal diols are cleaved by periodic acid to yield aldehydes or ketones, depending on the number of substituents on the carbon atoms bearing the hydroxyl groups. The periodic acid is reduced to iodic acid (HIO3 ).

What is the function of diol dehydrase?

Diol dehydrase converts vicinal diols such as 1,2-propanediol and 1,2-ethanediol to a geminal diol that dehydrates to the corresponding aldehyde.

Which reagents inactivate apoenzyme in diol dehydrase?

Several important amino acid residues have been identified in diol dehydrase by chemical modification. 116–120 The arginine-specific reagents 2,3-butanedione and phenylglyoxal inactivate apoenzyme but not holoenzyme.