Does Marfan syndrome cause depression?
Baeza-Velasco and colleagues [20] showed that certain diseases of connective tissue (e.g. Marfan and Ehlers-Danlos syndrome) may be associated with various psychiatric symptoms, such as those of anxiety and depression.
What are 5 of the characteristics and symptoms of Marfan syndrome?
Marfan syndrome features may include:
- Tall and slender build.
- Disproportionately long arms, legs and fingers.
- A breastbone that protrudes outward or dips inward.
- A high, arched palate and crowded teeth.
- Heart murmurs.
- Extreme nearsightedness.
- An abnormally curved spine.
- Flat feet.
How does Marfan syndrome affect emotional development?
MFS patients often have low self-esteem, lack of self-confidence, and a large percentage of them are introverted (7). One study found that more than 90% of MFS patients surveyed reported that sexual encounters were negatively affected by their disease (29). This can make it difficult for them to build relationships.
Does Marfan syndrome cause fatigue?
Marfan patients have a high level of fatigue and orthostatic complaints when compared to the general population. Fatigue and orthostatic tolerance are significantly correlated.
Are there different degrees of Marfan syndrome?
While most cases of Marfan syndrome are inherited, some are due to a spontaneous change in a gene, with no family history. Marfan syndrome can be mild to severe, and may become worse with age, depending on which area is affected and to what degree. In Marfan syndrome, the heart is often affected.
What limitations does a person with Marfan syndrome have?
People who have Marfan syndrome may be tall and thin with long arms, legs, fingers, and toes, as well as flexible joints. The most serious complications are problems in the heart and blood vessels, such as weakening or bulging of the aorta.
When is Marfan diagnosed?
Marfan syndrome is present at birth. However, it may not be diagnosed until adolescence or young adulthood.
What is the life expectancy for people with Marfan syndrome?
The cardiac complications, particularly aortic dilatation, dissection and rupture and involvement of the aortic and mitral valves, lead to a greatly reduced life expectancy. This poor survival was demonstrated in a series of 257 patients with the Marfan syndrome. The average age at death for the 72 deceased patients was 32 years.
What are the clinical features of Marfan’s syndrome?
Familial (autosomal dominant)
Can Marfan syndrome kill you?
Marfan syndrome can rupture the inner layers of the aorta, causing dissection that leads to bleeding in the wall of the vessel. Aortic dissection can be deadly. Surgery may be required to replace the affected part of the aorta.
Who is at risk for Marfan syndrome?
Marfan syndrome affects men and women equally and occurs among all races and ethnic groups. Because it’s a genetic condition, the greatest risk factor for Marfan syndrome is having a parent with the disorder. The pressure of blood leaving your heart can cause the wall of your aorta to bulge out, like a weak spot in a tire.