How common is haplogroup H?
Haplogroup H is the most common mtDNA clade in Europe. It is found in approximately 41% of native Europeans.
How many Mt haplogroups are there?
The current global mtDNA phylogenetic tree contains more than 4,000 different haplogroups (van Oven and Kayser, 2009).
How many mitochondrial DNA are there?
The mitochondrial genome contains 37 genes that encode 13 proteins, 22 tRNAs, and 2 rRNAs. The 13 mitochondrial gene-encoded proteins all instruct cells to produce protein subunits of the enzyme complexes of the oxidative phosphorylation system, which enables mitochondria to act as the powerhouses of our cells.
What are the aims of the 1000 Genomes Project?
The goal of the 1000 Genomes Project is to provide a resource of almost all variants, including SNPs and structural variants, and their haplotype contexts. This resource will allow genome-wide association studies to focus on almost all variants that exist in regions found to be associated with disease.
What happened to the 1000 Genomes Project data in the NCBI?
During the main 1000 Genomes Project, the NCBI acted as a mirror of the EBI hosted 1000 Genomes Project FTP site and also uploaded alignments and variant calls to an Amazon S3 bucket. This mirroring process stopped in September 2015. The NCBI FTP site and the Amazon S3 bucket still host 1000 Genomes Project data but no longer mirror new data.
What is the average distance between mtDNA genomes?
The average distance between mtDNA genomes is 3.8 × 10 −3 substitutions per site. The pattern of selection acting on individual mtDNA coding regions was examined by a comparison of the rate of synonymous (dS) and nonsynonymous (dN) changes per such site.
How do I use the 1000 Genomes Project on GRCh38?
Browse the 1000 Genomes Project phase three call set on GRCh37 Browse data from the 1000 Genomes Project samples and other data sets on GRCh38 View data for a specific variation and search by rsID Use a selection of tools to retrieve subsets of data, convert VCF to PED and calculate linkage disequilibrium
How will the genomes of 1000 unidentified individuals be sequenced?
The genomes of over 1000 unidentified individuals from around the world will be sequenced using next generation sequencing technologies. The results of the study will be publicly accessible to researchers worldwide.