How do you titrate insulin?
Titrating Insulin To normalize the FPG with long-acting basal insulin, it is safe to start empirically at 10 units daily or at a low dose of 0.15 U/kg/day. Patients should titrate the dose 2 units at a time every two to three days, based on SMBG, until the FPG is at goal.
How can I get my insulin titrate down?
Start basal insulin 10 units or 0.1-0.2 units/kg daily or divided BID. Titrate dose based on Fasting Plasma Glucose (FPG). Increase by 2-4 units or 10-15% every 3-4 days until FPG within target range, generally 80-130mg/dL (individualize).
How do you titrate mealtime insulin?
Regimen 2: Begin prandial insulin before each meal with a 50% basal/50% prandial ratio to achieve a TDD of 0.3–0.5 units/kg, starting at 50% of the TDD in three divided doses before meals.
How do you titrate premixed insulin?
Administer premix insulin analog immediately before or soon after the start of a meal. Titrate the dose preferably once or twice a week (see “Box 1”). Adjust the evening meal dose first, followed by the breakfast dose.
Why do you titrate insulin?
Ending Basal Insulin Titration Basal insulin is used to improve glycemic control with a focus on the overnight and fasting component of blood glucose management, but overall glycemic control and A1C levels are the result of a combination of both FPG and postprandial glucose (PPG) levels.
What is prandial insulin?
Prandial (bolus) insulin covers increases in blood glucose levels following meals [13]. The combination of basal and prandial therapy is an important option for patients with type 2 diabetes when glycemic control is not achieved with OADs alone or basal insulin plus OAD therapy [14].
How do you titrate basal bolus insulin?
Bolus insulin is initiated before the largest meal of the day at 4 units, 0.1 units/kg, or 10% of the basal dose. The dose is increased by 1–2 units or 10–15% once or twice weekly until the SMBG target is reached.
Is Humulin 70/30 and Lantus the same?
NPH (brand name Humulin N or Novolin N) is an intermediate-acting insulin that starts working in about 1 to 2 hours and can last from 16 to 24 hours. Insulin glargine (brand name Lantus) is a newer form of long-acting insulin. It starts to work within 1 to 2 hours and continues acting for about 24 hours.
What is the standard Humulin 70/30 dose?
There is no “standard” Humulin 70/30 dose that will work for all people or even for the same person in all situations. Humulin 70/30 is made up of two different insulins, 70 percent intermediate-acting (NPH insulin) and 30 percent short-acting (regular insulin). It is typically taken twice a day before meals (often about 30 minutes before eating).
What is humhumulin 70/30 made of?
Humulin 70/30 is made up of two different insulins, 70 percent intermediate-acting (NPH insulin) and 30 percent short-acting (regular insulin). It is typically taken twice a day before meals (often about 30 minutes before eating).
What should I look for in a Humulin your U-500 vial?
For the Humulin R U-500 vial, particular attention should be paid to the 20-mL vial size, prominent “U-500” and warning statements on the vial label, and distinctive coloring on the vial and carton. Dosing errors have occurred when Humulin R U-500 was administered with syringes other than a U-500 insulin syringe.
What is the target glucose for titration?
Target glucose for titration is fasting glucose.8,43,45,46,53 (may also consider post-dinner glucose when titrating dose)