Is Cystosarcoma Phyllodes malignant?
Reports have suggested, however, that about 85-90% of phyllodes tumors are benign and that approximately 10-15% are malignant. Although benign phyllodes tumors do not metastasize, they have a tendency to grow aggressively and can recur locally. Like other sarcomas, malignant phyllodes tumors metastasize hematogenously.
Is malignant phyllodes tumor curable?
Outlook for Phyllodes Tumors Your outlook is excellent if you had a benign tumor removed with surgery. Treatment often cures malignant phyllodes tumors, but they’re more likely to grow back. They can spread beyond your breast to your lungs.
Can phyllodes tumor turn into cancer?
Most phyllodes tumors are benign, but in rare cases they can be malignant (cancerous). In addition, their behavior is unpredictable. In rare cases, a benign tumor can recur (grow back) as a cancer.
Can phyllodes tumors be malignant?
Phyllodes tumors are most common in women in their 40s, but women of any age can have them. Women with Li-Fraumeni syndrome (a rare, inherited genetic condition) have an increased risk for phyllodes tumors. Most phyllodes tumors are benign (not cancer), but about 1 out of 4 of these tumors are malignant (cancer).
What is Cystosarcoma?
Clinically, cystosarcoma is a large (usually 3-5 cm in diameter) painless tumor with sudden growth acceleration especially during pregnancy. Cystosarcoma is usually circumscribed, containing firm and soft areas.
Can a fibroadenoma turn into a phyllodes tumor?
The transformation of a benign fibroadenoma into a phyllodes tumor is uncommon and unpredictable. We report the case of a 40-year-old woman with a core biopsy proven fibroadenoma that underwent transformation into a malignant phyllodes tumor after 3 years of size stability.
What is the treatment for malignant phyllodes tumor?
Local therapy for a phyllodes tumor will include surgery (wide excision or mastectomy) to remove the tumor and extra tissue around it. Sometimes, radiation is given as well. Systemic therapy (chemotherapy) may be used if a malignant phyllodes tumor has spread outside of the breast, though this not common.
Can a phyllodes tumor spread?
Phyllodes tumors tend to grow quickly, but they rarely spread outside the breast. Although most phyllodes tumors are benign (not cancerous), some are malignant (cancerous) and some are borderline (in between noncancerous and cancerous).
What does a phyllodes tumor feel like?
A phyllodes tumour can usually be felt as a smooth, hard lump in the breast. Sometimes it can be seen as a smooth bulge under the skin. Occasionally phyllodes tumours are fast-growing and become quite large. Phyllodes tumours are sometimes found during breast screening before they cause any noticeable symptoms.
Are phyllodes tumors moveable?
Phyllodes tumor is the most commonly occurring nonepithelial neoplasm of the breast, though it represents only about 1% of tumors in the breast. It has a smooth, sharply demarcated texture and typically is freely movable.
Can phyllodes spread?
What is Cystosarcoma phyllodes of the breast?
Background: Cystosarcoma phyllodes is a rare sarcoma of the breast. Although surgical removal is the mainstay of treatment, the extent of surgery required (excision vs. mastectomy) and the need for additional local therapy, such as radiotherapy, are unclear.
What is the surgical management of phyllodes tumors?
Surgical Management of Phyllodes Tumors. Tumor grade was categorized as low, intermediate, or high on the basis of 5 criteria: stromal cellularity, stromal atypia, microscopic appearance of the margin of tumor (infiltrating, effacing, or bulging), mitoses per 10 high-power fields, and macroscopic size of the tumor.
What are phyllodes tumors of the breast?
Phyllodes tumors of the breast are rare tumors that start in the connective (stromal) tissue of the breast. They get their name from the leaf-like pattern in which they grow (phyllodes means leaf-like in Greek). They are most common in women in their 30s and 40s, although women of any age can be affected.
What is the prognosis of phyllodes cancer?
If the tumor recurs locally, further surgery, including local excision or partial or total mastectomy typically results in a good outcome. The SArcoma and PHYllode Restrospective (SAPHYR) Study reported a three year survival rate for benign and borderline phyllodes tumors of 100 percent.
How common are palpable axillary lymph nodes in phyllodes?
Palpable axillary lymph nodes are encountered in 20% of patients with phyllodes tumors, but histological evidence of malignancy is encountered in less than 5% of axillary lymph node dissections for clinically positive nodes. The remainder of the findings are caused by necrosis of the primary tumor.