Is Fenoldopam used in hypertensive emergency?

Is Fenoldopam used in hypertensive emergency?

Conclusions: Fenoldopam safely and effectively lowers blood pressure in a dose-dependent manner in patients with hypertensive emergencies. Observations supporting potential risk factors for hypertensive emergency are discussed.

What is the treatment for hypertensive emergency?

In a hypertensive emergency, the first goal is to bring down the blood pressure as quickly as possible with intravenous (IV) blood pressure medications to prevent further organ damage. Whatever organ damage has occurred is treated with therapies specific to the organ that is damaged.

When do you use Fenoldopam?

Fenoldopam is indicated for in-hospital, short-term (up to 48 hours) management of severe hypertension when rapid, but quickly reversible, emergency reduction of blood pressure is clinically indicated, including malignant hypertension with deteriorating end-organ function.

What is the action of Fenoldopam?

Fenoldopam has a unique mechanism of action compared to other antihypertensive medications: it is a dopamine (D1) receptor agonist that results in decreased peripheral vascular resistance primarily in renal capillary beds, thus promoting increased renal blood flow, natriuresis, and diuresis.

What is corlopam used for?

Corlopam(Intravenous) Fenoldopam is used to quickly lower blood pressure for a short period of time. This medicine is usually given in an emergency situation, until you can be given other medicines to control your blood pressure. Fenoldopam may also be used for purposes not listed in this medication guide.

Is labetalol used in hypertensive emergency?

Labetalol is a unique alpha- and beta-adrenergic-receptor blocking agent that has recently been approved for the treatment of hypertensive emergencies and urgencies. This agent lowers peripheral vascular resistance by vasodilatation with little or no effect on cardiac output.

How do you administer labetalol injection?

If it is essential to reduce blood pressure quickly, a dose of 50mg of labetalol hydrochloride should be given by intravenous injection (over a period of at least one minute) and, if necessary, may be repeated at five minute intervals until a satisfactory response occurs. The total dosage should not exceed 200mg.

What is the mechanism of action of Fenoldopam?

How is Fenoldopam administered?

Fenoldopam administration is via a continuous intravenous (IV) infusion using an infusion pump. Initiate treatment at 0.01 to 0.3 mcg/kg/minute then increase by 0.05 to 0.1 mcg/kg/minute at 15 minute intervals until desired blood pressure is reached or a max of 1.6 mcg/kg/minute is reached.

What are the contraindications of Fenoldopam?

Contraindications / Precautions

• Asthma, sulfite hypersensitivity. Certain formulations of fenoldopam contain sodium metabisulfite.
• Glaucoma, increased intraocular pressure.
• Geriatric.
• Pregnancy.
• Breast-feeding.