Is NS1 antigen specific for dengue?
NS1 Ag assay is useful, sensitive and specific for the diagnosis of dengue infection, especially during the acute phase when antibodies are not detectable and the dengue serology was negative. Early diagnosis and timely intervention can reduce the mortality due to severe dengue infection.
What is the meaning of NS1 antigen?
NS1 antigen test (nonstructural protein 1), is a test for dengue, introduced in 2006. It allows rapid detection on the first day of fever, before antibodies appear some 5 or more days later. It has been adopted for use in some 40 nations. The method of detection is through enzyme-linked immunosorbent assay.
What is the amount of sensibility of NS1 in primary infection?
In primary infections, the InBios NS1 kit demonstrated a higher sensitivity (98.8%) than in secondary infections (83.5%).
What is normal value of NS1 antigen?
The positive predictive value of a NS1 antigen positivity between days 5-6 of illness and development of severe clinical disease was 63.6 (95% confidence interval 49.6 to 76.1) and the negative predictive value was 63.2 (95% confidence interval 49.3 to 75.5).
When should NS1 test be done?
Avinash Phadke Labs, “The NS1 test should be taken on the very first day of the fever striking. It holds relevance after 24 hours also, but ideally should be taken within 24 hours.”
What is the confirmatory test for dengue?
Nucleic acid amplification tests (NAATs) Presence of virus by rRT-PCR or NS1 antigen in a single diagnostic specimen is considered laboratory confirmation of dengue in patients with a compatible clinical and travel history.
How do you treat an NS1 antigen test?
The NS1 antigen test is the most effective for early diagnosis of dengue infection. The main focus of treatment is to ensure that the patient gets adequate hydration. Acetaminophen (paracetamol) is used to manage the fever. If the symptoms are treated properly, the patient should recover in around two weeks.
What is dengue IgG IgM and NS1?
The dengue antigen NS1, IgG & IgM test measures the dengue virus or antibodies which are produced in response to dengue infection. Dengue fever is a viral infection which is transmitted to humans by mosquitoes which live in tropical and subtropical climates and are responsible for carrying the virus.