Is telaprevir discontinued?
Vertex pharmaceuticals discontinued the sales and distribution of telaprevir in the United States in October 2014, primarily due to available alternative treatments and diminishing market demands. The drug telaprevir was formerly known as VX-950 and was co-developed by Vertex Pharmaceuticals and Johnson & Johnson.
What type of drug is telaprevir?
Telaprevir is in a class of medications called protease inhibitors. It works by decreasing the amount of hepatitis C virus (HCV) in the body.
Who makes telaprevir?
Telaprevir (VX-950), marketed under the brand names Incivek and Incivo, is a pharmaceutical drug for the treatment of hepatitis C co-developed by Vertex Pharmaceuticals and Johnson & Johnson. It is a member of a class of antiviral drugs known as protease inhibitors.
What does telaprevir treat?
Telaprevir is approved for use in combination with peginterferon and ribavirin to treat adults with genotype 1 chronic hepatitis C infection and compensated liver disease.
When was telaprevir approved by FDA?
May 23, 2011 — The US Food and Drug Administration (FDA) has approved telaprevir (Incivek, Vertex) for the treatment of hepatitis C virus (HCV) infection. The approval comes 1 week after the approval of boceprevir (Victrelis, Merck), also for HCV, and is the second drug to be approved for HCV in 20 years.
Is saquinavir a protease inhibitor?
AIDS: Saquinavir, developed by Hoffmann-LaRoche under the trade name Invirase, is the first protease inhibitor to be approved by the Food and Drug Administration (FDA) for use in combination with one or more unspecified nucleoside analogs.
Who can not take ribavirin?
Ask your doctor about any risk. Ribavirin is not approved for use by anyone younger than 3 years old. Ribavirin tablets are not approved for use by anyone younger than 5 years old.
What class of drug is ribavirin?
Ribavirin is in a class of antiviral medications called nucleoside analogues. It works by stopping the virus that causes hepatitis C from spreading inside the body.
How do I know if I am allergic to telaprevir?
If you have an allergy to telaprevir or any other part of telaprevir. If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
What should I avoid while taking telaprevir?
If you are not taking ribavirin or peginterferon alfa. If you have liver disease . If you take any drugs (prescription, OTC, natural products, vitamins) that must not be taken with telaprevir, like certain drugs that are used for high cholesterol, seizures, migraines, or rifampin.
How long does telaprevir stay in your system?
Telaprevir has a half-life of elimination of 4.0-4.7 hours after a single dose and an effective half life of 9-11 hours at steady state Label.
How do I know if I have an allergy to ribavirin?
Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you are not taking ribavirin or peginterferon alfa.