Is there a generic for Dolutegravir?
SILVER SPRING, Md. — The Food and Drug Administration has granted its tentative approval to Aurobindo Pharma for its generic of Tivicay (dolutegravir or DTG), making it the first approval for a generic of the HIV treatment recommended by the World Health Organization and the Centers for Disease Control and Prevention.
Is there a generic for Tivicay?
No. There is currently no therapeutically equivalent version of Tivicay available in the United States. Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Tivicay. These medications may be counterfeit and potentially unsafe.
How much does Dolutegravir cost?
Current prescription drug costs
| Drug name (brand name) | Cost of brand name | Strength |
|---|---|---|
| dolutegravir (Tivicay) | $1,658–$1,989 | 50 mg |
| maraviroc (Selzentry) | $1,511–$1,813 | 300 mg |
| enfuvirtide (Fuzeon) | $3,586–$4,303 | 90 mg |
| abacavir/lamivudine (Epzicom) | $1,292–$1,550 | 600 mg/300 mg |
What is the brand name for Dolutegravir?
Dolutegravir comes in tablet form in the following strengths: 5-mg tablet for oral suspension (brand name: Tivicay PD) 10-mg, 25-mg, and 50-mg tablets (brand name: Tivicay)
Why is efavirenz better than dolutegravir?
The integrase inhibitor dolutegravir reduces HIV viral load to less than 50 copies per mL after a median of 28 days in non-pregnant adults, compared with 84 days for efavirenz.
Does dolutegravir cause liver damage?
Dolutegravir is used only in combination with other antiretroviral agents in the treatment of HIV infection, and it has had limited use. Dolutegravir is associated with a low rate of serum aminotransferase elevations during therapy, but has not been linked to instances of acute, clinically apparent liver injury.
Does dolutegravir have side effects?
Insomnia, dizziness, headache and other central nervous system side-effects are occurring more frequently with everyday use of dolutegravir than clinical trials had suggested, and are most likely to occur in women, people over 60 and people starting abacavir at the same time, a German research group told the …
When is Triumeq generic?
Triumeq was eligible for patent challenges on August 12, 2017. By analyzing the patents and regulatory protections it appears that the earliest date for generic entry will be December 8, 2029.
When should I take Dolutegravir?
It is usually taken once or twice a day with or without food. Take dolutegravir at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take dolutegravir exactly as directed.
What are side effects of Dolutegravir?
Side effects of Dolutegravir may include.
- Increased cholesterol and triglycerides.
- Increased lipase.
- High blood sugar (hyperglycemia)
- Increased creatinine kinase.
- Increased AST.
- Insomnia.
- Increased ALT.
- Increased bilirubin.
What is the best time to take dolutegravir?
Dolutegravir is best taken in the morning or during the day. This is because it can stop you sleeping if you take it at night. 50 mg twice-daily dose is needed in people using dolutegravir in combination with efavirenz, nevirapine, tipranavir/ritonavir, or rifampicin.
Is efavirenz same as dolutegravir?
Efavirenz 400mg was recommended as an alternative option for first-line treatment by the World Health Organization in 2016 but there has been no head-to-head comparison with dolutegravir. This leaves national treatment programmes with a dilemma, for dolutegravir has been shown to be superior to efavirenz 600mg.