What are A549 cells?
A549 cells are adenocarcinomic human alveolar basal epithelial cells, and constitute a cell line that was first developed in 1972 by D. J. Giard, et al. The cells are used as models for the study of lung cancer and the development of drug therapies against it.
What are A549 cells used for?
The A549 cells have been used to model the alveolar Type II pulmonary epithelium. Studies have shown that this can be particularly useful in research for studying the metabolic processing of lung tissue and for identifying mechanisms of drug delivery to the tissue.
What is the size of A549 cells?
14.93 μm
Results: (1) The diameter of A549 cells from inverted microscopy and TEM images was 14.93 μm and 10.59 μm. (2) By defining cell as reference space the volume densities (VV) of nucleus and cytoplasm were about 0.28 and 0.72; the surface densities (SV) of nucleus were 0.19 μm-1.
What are H1299 cells?
H1299, also known as NCI-H1299 or CRL-5803, is a human non-small cell lung carcinoma cell line derived from the lymph node, which is widely used in research. As with other immortalized cell lines, H1299 cells can divide indefinitely.
Is A549 a NSCLC?
One commonly used line is A549, an epithelial carcinoma derived from a 58 year old male patient, known to be KRAS mutant and EGFR wild type. At Labcorp we have been using A549 as a model of NSCLC for more than 10 years.
Is A549 a Nsclc?
What are SW480 cells?
Human SW480 cell line has been used to study the antiproliferative effects of F. mughlea Pesmen on cancer cells. It has also been used as an in vitro model to study key cellular processes required for metastasis.
How long do fibroblasts take to attach?
while performing this I make preplate step to eliminate fibroblast and it takes only 2 hours for attachment of almost all of fibroblast.
What are a549-dual™ cells?
A549-Dual™ cells are adherent epithelial cells that have been derived from the human A549 lung carcinoma cell line by stable integration of two inducible reporter constructs. The A549 cell line is a well-characterized cellular model for asthma, allergies and respiratory infections.
Is A549 a cancer cell line?
Although A549 is a cancer cell line, it has also been studied for its response to tuberculosis, specifically the production of chemokines as it is induced by the invading bacteria. ^ a b c d “A549 Cell Line: Human alveolar adenocarcinoma cell line -General Information”.
What is the cytogenetic information for A549?
A549 Cytogenetic Information. The cell line is hypotriploid with a modal chromosome number of 66, which occurs in 24% of cells.
What does A549 stand for?
A549 cells are adenocarcinomic human alveolar basal epithelial cells, and constitute a cell line that was first developed in 1972 by D. J. Giard, et al. through the removal and culturing of cancerous lung tissue in the explanted tumor of a 58-year-old caucasian male. The cells are used as models for the study…