What can a pregnant person take for depression?
Generally, these antidepressants are an option during pregnancy: Certain selective serotonin reuptake inhibitors (SSRIs). SSRIs are generally considered an option during pregnancy, including citalopram (Celexa) and sertraline (Zoloft). Potential complications include maternal weight changes and premature birth.
Do SSRIs cross the placenta?
SSRI/ SNRI antidepressants cross the placenta, the blood-brain barrier and pass into the milk and they increase the levels of monoamines in the brain. These can then affect the functional development of the brain and the behavior of the child.
Can depression pills cause miscarriage?
Conclusions: Antidepressant use in the first trimester is associated with an increased risk of miscarriage when compared with either nondepressed or depressed unexposed women, even after accounting for induced abortions.
What’s the safest antidepressant in pregnancy?
Antidepressants that are considered safer include:
- Fluoxetine (Prozac, Sarafem)
- Citalopram (Celexa)
- Sertraline (Zoloft)
- Amitriptyline (Elavil)
- Desipramine (Norpramin)
- Nortriptyline (Pamelor)
- Bupropion (Wellbutrin)
Can being sad affect my unborn baby?
Depression during pregnancy can also lead to: miscarriage, delivering before the due date (preterm), giving birth to a small baby (low birth weight).
How do antidepressants affect a fetus?
It’s important for a mother and her doctor to know the risks. About 30 percent of babies whose mothers take SSRIs will experience neonatal adaptation syndrome, which can cause increased jitteriness, irritability and respiratory distress (difficulty breathing), among other symptoms.
Is Zoloft linked to miscarriage?
June 2, 2010 — A Canadian study of more than 5,000 women shows an association between taking antidepressants, particularly the selective serotonin reuptake inhibitors (SSRIs) such as Paxil, Prozac, and Zoloft, and an increased risk for miscarriage.
Can you breastfeed on Zoloft?
Yes, Zoloft can pass into breast milk. While more research is needed in this area, current research indicates that only a very small amount passes through. (Peak levels in the hindmilk were typically found 8 to 9 hours after a dose.)
Does the HTR2A functional rs6311 polymorphism modulate the severity of major depression?
Data suggest that the HTR2A functional rs6311 polymorphism, which other studies have associated with differential HTR2A mRNA expression, may modulate the severity of depression symptoms in children with autism spectrum disorder. 5-HT2A receptor clusters in peripheral lymphocytes are altered in major depression.
Does HTR2A influence MDD susceptibility and antidepressant therapeutic response?
These tests can identify genes with genome-wide significance, but no single SNP effect is able to give genome-wide significance by univariate tests. Thus, the hypothesis that HTR2A may influence MDD susceptibility and antidepressant therapeutic response is verified with gene-based analysis of genome-wide data.
What is the role of HTR2A in the pathophysiology of major depressive disorder?
The genetic effects of HTR2A in MDD susceptibility and antidepressant therapeutic response have been tested by many genetic studies, as 5-HT2A plays an important role in the pathogenesis of MDD as well as in the mechanism of antidepressant medication.
What are the risks of depression during pregnancy?
There are many different factors that can add to your risk of developing depression during your pregnancy. These risks can include: Having a history of depression or premenstrual dysphoric disorder (PMDD). Your age at time of your pregnancy — the younger you are, the higher the risk.