What class of drug is Primaxin?
This medication is used to treat a wide variety of bacterial infections. This medication is known as a carbapenem-type antibiotic.
What bacteria does primaxin cover?
Imipenem is active against aerobic and anaerobic Gram positive as well as Gram negative bacteria including Pseudomonas aeruginosa and the Enterococcus.
What is the generic name for Primaxin?
GENERIC NAME: IMIPENEM/CILASTATIN – INJECTION (IM-i-PEM-em/SYE-la-STAT-in)
What drug class is meropenem?
Meropenem injection is in a class of medications called antibiotics. It works by killing bacteria that cause infection. Antibiotics such as meropenem injection will not work for colds, flu, or other viral infections.
Can you give Primaxin?
PRIMAXIN I.M. is for intramuscular use only. Patients with lower respiratory tract infections, skin and skin structure infections, and gynecologic infections of mild to moderate severity may be treated with 500 mg or 750 mg administered every 12 hours depending on the severity of the infection.
When do you use Primaxin?
To reduce the development of drug-resistant bacteria and maintain the effectiveness of PRIMAXIN and other antibacterial drugs, PRIMAXIN should be used only to treat infections that are proven or strongly suspected to be caused by susceptible bacteria.
Is primaxin a broad spectrum antibiotic?
Antimicrobial Activity. Imipenem and meropenem have an exceptionally broad spectrum of activity. The bacterial species considered resistant to these drugs are MRSA, methicillin-resistant S.
Is primaxin a beta lactam antibiotic?
Imipenem (trade name Primaxin among others) is an intravenous β-lactam antibiotic discovered by Merck scientists Burton Christensen, William Leanza, and Kenneth Wildonger in the mid-1970s.
How does primaxin work?
It works by killing bacteria. Cilastatin is in a class of medications called dehydropeptidase inhibitors. It works by helping imipenem stay active in your body for a longer period of time. Antibiotics such as imipenem and cilastatin injection will not work for colds, flu, or other viral infections.
Who should not take meropenem?
Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of meropenem injection in children 3 months of age and older with complicated skin and skin structure infections and bacterial meningitis, and for children with intra-abdominal infections.
Is meropenem the strongest antibiotic?
Meropenem (Merrem) is considered one of the stronger antibiotics. It works against many types of bacteria and treats severe or complicated infections when other antibiotics may not be enough.
What should you assess before giving Primaxin?
Before initiating therapy with PRIMAXIN, careful inquiry should be made concerning previous hypersensitivity reactions to penicillins, cephalosporins, other beta-lactams and other allergens. If an allergic reaction to PRIMAXIN occurs, discontinue the drug immediately.
What is Primaxin IV?
PRIMAXIN I.V. (Imipenem and Cilastatin for Injection) is a sterile formulation of imipenem (a thienamycin antibiotic) and cilastatin sodium (the inhibitor of the renal dipeptidase, dehydropeptidase l), with sodium bicarbonate added as a buffer.
What is the half-life of Primaxin?
intravenous infusion of PRIMAXIN I.V. range from 15 to 25 µg/mL for the 250 mg dose, from 31 to 49 µg/mL for the 500 mg dose, and from 56 to 88 µg/mL for the 1000 mg dose. The plasma half-life of each component is approximately 1 hour.
Is Primaxin safe for children with CNS infections?
PRIMAXIN is not recommended in pediatric patients with CNS infections because of the risk of seizures [see Dosage and Administration (2.2), Warnings and Precautions (5.2), and Use in Specific Populations (8.4) ].
What are the dosage recommendations for Primaxin (imipenem)?
The dosage recommendations for PRIMAXIN represent the quantity of imipenem to be administered. An equivalent amount of cilastatin is also present in the solution. These doses should be used for patients with creatinine clearance of greater than or equal to 90 mL/min.