What does niacin inositol Hexanicotinate do?
Inositol hexanicotinate has a proven beneficial effect on endothelium-dependent vasodilatation (widening of blood vessels), thus it improves blood flow in conditions where it is compromised. In Europe it is often prescribed for the symptomatic relief of Raynaud’s phenomenon and severe intermittent claudication.
Is inositol Hexanicotinate the same as niacin?
Inositol nicotinate, also known as Inositol hexaniacinate/hexanicotinate or “no-flush niacin”, is a niacin ester and vasodilator. It is used in food supplements as a source of niacin (vitamin B3), where hydrolysis of 1 g (1.23 mmol) inositol hexanicotinate yields 0.91 g nicotinic acid and 0.22 g inositol.
What does no-flush niacin do?
Nicotinic acid is known to lower two types of “bad” cholesterol (LDL and VLDL) as well as increase levels of “good” cholesterol (HDL). In fact, it is able to increase HDL more than any other medication.
Is no-flush niacin bad for your liver?
Is it dangerous? Niacin flush is harmless. However, high doses of niacin can cause other, more dangerous side effects, although these are rare (20). The most harmful of these is liver damage.
Can you take inositol long term?
In addition, it’s unclear whether inositol supplements are safe for long-term use. In most studies, inositol supplements were only taken for a year or less. As with any supplement, talk to your doctor before taking inositol. Inositol supplements are associated with very few and only mild adverse effects.
How long does niacin flush last?
Other than causing discomfort the flushing is harmless and usually subsides within 1 or 2 hours. Symptoms are most intense after the first dose and typically diminish over days or weeks with continued use of niacin.
Is 500 mg of inositol Hexanicotinate safe?
When taken by mouth: Inositol nicotinate is POSSIBLY SAFE for most people. It can cause some side effects such as stomach upset, intestinal gas, and nausea. It might also cause liver damage like other niacin products in some people.
What is extended release niacin?
Extended-release niacin (niacin ER; Niaspan), Kos Pharmaceuticals, Inc.) is a prescription formulation of niacin, administered once-daily at bedtime. Niacin ER is as effective in modifying lipoprotein levels as an equal daily dose of niacin IR and it causes less flushing.
Is non flush niacin as effective as regular niacin?
An excellent study by researchers at the University of Washington School of Medicine showed that taking no-flush niacin generates virtually no free nicotinic acid, and has little or no effect on HDL. No-flush niacin lives up to the no-flush part of its name because it isn’t providing the body with any niacin.
Does niacin hurt your kidneys?
For people with kidney disease: Ask your doctor whether niacin is safe for you to take. Niacin is processed by your kidneys. If you have kidney disease, the levels of niacin in your blood can get too high. This could cause you to have more side effects.
What are the side effects of inositol?
Inositol is generally considered safe in adults. Side effects, if any, tend to be mild and may include nausea, stomach pain, tiredness, headache, and dizziness. Most side effects occur with doses greater than 12 grams per day. The metabolic effects of inositol may not be appropriate for everyone.
What does flush free niacin do?
Flush-free niacin is able to dilate blood vessels and has been used the treatment of diseases, such as Raynaud’s disease. Experiments using nicotinic acid are plentiful; however, studies examining the effectiveness of inositol hexaniacinate alone in lowering cholesterol levels are few.
Will flush free niacin clean your system?
So the flush-free niacin product offers a capsule delivery system and it recommends 3 capsules spread throughout the day to give similar cholesterol support benefits without worrying about the flushing effect.
What are the benefits of no flush niacin?
Since there are niacin side effects associated with taking nicotinic acid products, you may want to use no-flush niacin, or flush-free niacin, to lower your cholesterol. Niacin, or vitamin B-3, is a supplement known for its ability to lower cholesterol and prevent heart disease.
What are the side effects of niacin flush?
Commonly reported side effects of niacin include: pruritus, nausea, and flushing. Other side effects include: skin rash, and vomiting.