What does Stargardt disease look like?
The most common symptom of Stargardt disease is a slow loss of central vision in both eyes. Some people lose their central vision more quickly than others. Other symptoms may include: Gray, black, or hazy spots in the center of your vision.
What is fundus Flavimaculatus?
Fundus flavimaculatus (FFM) is a Stargardt-like condition that is later-onset and slow-progressing. FFM presents with white or yellowish-white pisciform flecks possibly with foveal atrophy. While no treatment is available, studies are investigating novel treatment options.
How fast does Stargardt progress?
How Fast Does Stargardt’s Progress? Vision loss from Stargardt’s generally begins to show up within the first 20 years of a young person’s life, particularly in early childhood.
What is the difference between Stargardt disease and macular degeneration?
Stargardt disease is an inherited form of macular degeneration. While it affects the same part of the central retinal, called the macula, as age-related macular degeneration (AMD), it is different from AMD.
Is there any cure for Stargardt’s disease?
At this time there is no treatment available for Stargardt disease. However, researchers are studying gene and drug therapies. One promising study involves delivering a healthy version of the gene that causes Stargardt disease, ABCA4, into retinal cells to restore production of the normal protein.
What is fundus eye test?
obtain a better view of the fundus of eye. Dilated fundus examination or dilated-pupil fundus examination (DFE) is a diagnostic procedure that employs the use of mydriatic eye drops (such as tropicamide) to dilate or enlarge the pupil in order to obtain a better view of the fundus of the eye.
What is fundus disease?
Fundus albipunctatus is an eye disorder characterized by an impaired ability to see in low light (night blindness) and the presence of whitish-yellow flecks in the retina, which is the specialized light-sensitive tissue in the inner lining of the back of the eye (the fundus).
What is fundus autofluorescence test?
Fundus autofluorescence (FAF) is a non-invasive imaging technique that detects fluorophores, naturally occurring molecules that absorb and emit light of specified wavelengths [1].
What does vision look like with macular degeneration?
Individuals with vision loss from age-related macular degeneration look fine. Their eyes appear to be just like they always were and their peripheral (side) vision is preserved, so they can walk around with little or no difficulty and may even spot a small dark button dropped on a light rug.
What is the difference between Stargardt’s disease and fundus flavimaculatus?
A study of 67 patients with a diagnosis of Stargardt’s disease (juvenile macular degeneration) or fundus flavimaculatus showed that, apart from the ophthalmoscopic appearance, there is no clear distinction between these two disorders.
What is the prognosis of fundus flavimaculatus (FF)?
Patients with fundus flavimaculatus often have a later disease onset and slower visual deterioration, making fundus flavimaculatus a milder condition. Surprisingly, comparing fundus photographs of both conditions, one might get the opposite impression because in fundus flavimaculatus there is more widespread retinal involvement.
What is Stargardt disease and what causes it?
The disease causes progressive damage — or degeneration — of the macula, which is a small area in the center of the retina that is responsible for sharp, straight-ahead vision. Stargardt disease is one of several genetic disorders that cause macular degeneration. Experts estimate that 1 in 8-10 thousand people have Stargardt disease.
What are stgd3-like macular dystrophies (stgd3)?
Stargardt-like macular dystrophies (STGD3, OMIM #600110) involving dominant mutations in the ELOVL4 gene (6q14.1) present with overlapping clinical features but are not currently classified as typical Stargardt disease.