What drugs interact badly with methadone?
Key Messages
| Medicine Classification | Examples | Effect |
|---|---|---|
| Anticonvulsants | carbamazepine, phenobarbitone, phenytoin | Reduced methadone levels |
| Antibiotics | rifampicin | |
| Non-Nucleoside Reverse -Transcriptase Inhibitors | efavirenz, nevirapine | |
| Azole antifungals | fluconazole, ketoconazole | Increased methadone levels |
Which medication is not administered with digoxin?
The adverse effects of digoxin are potentiated by renal impairment, which may be pre-existing or due to nephrotoxic drugs such as nonsteroidal antiinflammatory drugs (NSAIDs), angiotensin-converting-enzyme (ACE) inhibitors, angiotensin II receptor antagonists and ciclosporin.
Can you mix methadone and traMADol?
Using methadone together with traMADol can lead to serious side effects including seizures, respiratory distress, coma, and even death. Combined use can also increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect.
What medicines Cannot be taken together?
Dangerous and Deadly Drug Combinations
- Dangerous and Deadly Drug Combinations. Douglas S.
- Drug/Drug Interactions.
- St John’s Wort and Potentially Lifesaving Drugs.
- Serotonin Syndrome.
- Statins Plus CYP3A4 Inhibitors.
- Clarithromycin and Calcium-Channel Blockers.
- TMP/SMX and Antihypertensive Agents.
- Warfarin and Acetaminophen.
What medications can’t be taken together?
What Drugs Can You Not Take Together?
- Two or more drugs that share an active ingredient. You could have side effects or an overdose.
- Blood-thinning drugs with NSAIDs. Your odds for a dangerous bleed could go up.
- Pills with antihistamines.
Which medication can interfere with absorption of digoxin?
Drugs which reduce digoxin absorption include the antacids aluminium hydroxide, magnesium hydroxide and magnesium trisilicate, the antidiarrhoeals kaolin and pectin, the hypocholesterolaemic agent cholestyramine and the chemotoxins cyclophosphamide, vincristine and bleomycin.
Can you take digoxin and aspirin together?
aspirin digoxin You may need dose adjustments or special tests in order to safely take both medications together. This combination may increase digoxin levels.
Which drug is interact with digoxin and increase digoxin levels?
In selected patients, antibiotics may enhance digoxin bioavailability by eliminating intestinal flora that metabolize digoxin. Antiarrhythmic drugs, such as quinidine and amiodarone, can markedly increase steady state serum digoxin levels.