What is a common complication of extravasation of chemotherapy medications intended for IV administration?

What is a common complication of extravasation of chemotherapy medications intended for IV administration?

Extravasation is known to cause a mostly painful ulceration, local paresthesia and slow healing[9,32]. It can cause significant irritation and usually presents with intense pain around intravenous line or port site, erythema and tenderness[32].

How do you treat extravasation of contrast?

How Is Contrast Extravasation Treated? If contrast extravasation happens, we will have you raise your arm above the level of your heart and apply a cold compress to the IV site. An ice pack also helps to limit any pain you may have—both while you are at the medical center and over the next few days.

How is extravasation of chemotherapy treated?

Hyaluronidase has been used for the treatment of vinca alkaloid and taxane extravasations. Doses of hyaluronidase ranging from 150 to 1,500 units diluted in 1 mL of normal saline subcutaneously or intradermally within 1 hour of extravasation have been used.

What is extravasation in chemotherapy?

Extravasation is a term that describes a drug inadvertently or accidentally leaking into surrounding tissue or the subcutaneous space during IV infusions.

What is chemotherapy extravasation?

What do you do after extravasation?

If extravasation occurs, the injection should be stopped immediately and the IV tubing disconnected. Avoid applying pressure to the site, and do not flush the line. Leave the original catheter in place, and attempt to aspirate as much of the infiltrated drug as possible.

What is chemo antidote?

Uridine triacetate (Vistogard—Wellstat Therapeutics Corporation; BTG)—the first and only antidote for emergency treatment following an overdose of select chemotherapy agents—was approved by FDA in mid-December. The agent, a pyrimidine analog, is a prodrug of uridine that inhibits cell damage and death.