What is BeneFIX used for?
This medication is used to prevent or control bleeding in people with little or no factor IX (due to hemophilia B, Christmas disease). Factor IX is a protein (clotting factor) in the blood that works with other clotting factors to help the blood clot and stop bleeding.
How is BeneFIX administered?
BeneFIX is administered by intravenous infusion after reconstitution of the lyophilised powder for solution for injection with sterile 0.234% sodium chloride solution (see section 6.6). BeneFIX should be administered at a slow infusion rate. In most of the cases, an infusion rate of up to 4 mL per minute has been used.
How do you give BeneFIX?
Perform venipuncture. Insert the needle on the infusion set tubing into the vein, and remove the tourniquet. Inject the reconstituted BeneFIX intravenously over several minutes. Adjust the rate of administration based on the patient’s comfort level.
What is the cost of BeneFIX?
The lowest GoodRx price for the most common version of Benefix is around $4,236.30, 63% off the average retail price of $11,655.05. Compare coagulation factors.
How is Idelvion administered?
2.3 Administration For intravenous injection only. of each patient, not exceeding 10 mL per minute. Administer IDELVION at room temperature and within 4 hours of reconstitution. Discard any unused product.
Who owns benefix?
Matt Ranauro – Founder
Matt Ranauro – Founder/CEO – benefix | LinkedIn.
What is the half life of benefix?
The pharmacokinetic characteristics of BeneFIX were also assessed in 23 of these patients. The mean increase in circulating FIX activity was 0.72 IU/dL per IU/kg infused (range 0.39, 1.24) and the mean plasma FIX half-life 22 h (range 13, 35).
What is the half life of BeneFIX?
Why is clotting factor so expensive?
Not only do prices rise steadily as each new product comes on the market, demand is growing — and pushing costs upward — as more and more clotting factor is used to prevent bleeding episodes, not just to treat them.
Is hemophilia treatment expensive?
The cost of drug therapy for a person with hemophilia can be several hundred thousand dollars per year and annual treatment costs of $1 million or more are not unheard of for patients with the most severe forms of the disease.
Who makes benefix?
for Health Care Professionals: BENEFIX U.S. Physician Prescribing Information. BENEFIX U.S. Medical Information Page – clinical & safety information, ways to contact Pfizer Medical & other resources.
What is the half life of Idelvion?
The mean half-life of Idelvion was 91.4 hours, confirming the results of the pivotal trial. Around 89 percent of bleeds were successfully managed with one injection.
How do I use the BenefiX vial?
Connect the diluent syringe to the vial adapter by inserting the tip into the adapter opening while firmly pushing and turning the syringe clockwise until secured. Slowly depress the plunger rod to inject all the diluent into the BeneFIX vial. Without removing the syringe, gently swirl the contents of the vial until the powder is dissolved.
What is BenefiX used to treat?
Please see full Prescribing Information for BeneFix. BeneFix, Coagulation Factor IX (Recombinant), is an injectable medicine that is used to help control and prevent bleeding in people with hemophilia B. Hemophilia B is also called congenital factor IX deficiency or Christmas disease.
How do you administer BenefiX infusion?
Insert the needle on the infusion set tubing into the vein, and remove the tourniquet. Inject the reconstituted BeneFIX intravenously over several minutes. Adjust the rate of administration based on the patient’s comfort level. Note: Agglutination of red blood cells in the tubing/syringe has been reported with the administration of BeneFIX.
What is the recommended infusion rate for the use of basebenefix?
BeneFIX should be administered at a slow infusion rate. In most of the cases, an infusion rate of up to 4 mL per minute has been used. The rate of administration should be determined by the patient’s comfort level.